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2WDT
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BU of 2wdt by Molmil
Crystal structure of Plasmodium falciparum UCHL3 in complex with the suicide inhibitor UbVME
Descriptor: CHLORIDE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3
Authors:Weihofen, W.A, Artavanis-Tsakonas, K, Gaudet, R, Ploegh, H.L.
Deposit date:2009-03-26
Release date:2009-12-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
J.Biol.Chem., 285, 2010
3DCG
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BU of 3dcg by Molmil
Crystal Structure of the HIV Vif BC-box in Complex with Human ElonginB and ElonginC
Descriptor: Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, Virion infectivity factor
Authors:Stanley, B.J, Ehrlich, E.S, Short, L, Yu, Y, Xiao, Z, Yu, X.-F, Xiong, Y.
Deposit date:2008-06-03
Release date:2008-07-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly
J.Virol., 82, 2008
3DBL
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BU of 3dbl by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190wt-NEDD8Ala72Gln)
Descriptor: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
Authors:Souphron, J, Schulman, B.A.
Deposit date:2008-06-01
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008
3DBR
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BU of 3dbr by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Gln-NEDD8Ala72Arg)
Descriptor: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
Authors:Souphron, J, Schulman, B.A.
Deposit date:2008-06-02
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008
2XBB
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BU of 2xbb by Molmil
Nedd4 HECT:Ub complex
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE NEDD4, GLYCEROL, UBIQUITIN
Authors:Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S.
Deposit date:2010-04-08
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
1NBF
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BU of 1nbf by Molmil
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Descriptor: Ubiquitin aldehyde, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y.
Deposit date:2002-12-02
Release date:2003-01-07
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Cell(Cambridge,Mass.), 111, 2002
1P3Q
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BU of 1p3q by Molmil
Mechanism of Ubiquitin Recognition by the CUE Domain of VPS9
Descriptor: Ubiquitin, Vacuolar protein sorting-associated protein VPS9
Authors:Prag, G, Misra, S, Jones, E.A, Ghirlando, R, Davies, B.A, Horazdovsky, B.F, Hurley, J.H.
Deposit date:2003-04-18
Release date:2003-06-24
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of Ubiquitin Recognition by the CUE Domain of Vps9p.
Cell(Cambridge,Mass.), 113, 2003
1Q0W
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BU of 1q0w by Molmil
Solution structure of Vps27 amino-terminal UIM-ubiquitin complex
Descriptor: Ubiquitin, Vacuolar protein sorting-associated protein VPS27
Authors:Swanson, K.A, Kang, R.S, Stamenova, S.D, Hicke, L, Radhakrishnan, I.
Deposit date:2003-07-17
Release date:2003-10-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of Vps27 UIM-Ubiquitin Complex Important for Endosomal Sorting and Receptor Downregulation
Embo J., 22, 2003
1P9D
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BU of 1p9d by Molmil
High-resolution structure of the complex of HHR23A ubiquitin-like domain and the C-terminal ubiquitin-interacting motif of proteasome subunit S5a
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, UV excision repair protein RAD23 homolog A
Authors:Mueller, T.D, Feigon, J.
Deposit date:2003-05-10
Release date:2003-10-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural determinants for the binding of ubiquitin-like domains to the proteasome.
Embo J., 22, 2003
1OTR
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BU of 1otr by Molmil
Solution Structure of a CUE-Ubiquitin Complex
Descriptor: Ubiquitin, protein Cue2
Authors:Kang, R.S, Daniels, C.M, Salerno, W.J, Radhakrishnan, I.
Deposit date:2003-03-22
Release date:2003-06-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of a CUE-Ubiquitin Complex Reveals a Conserved Mode of Ubiquitin Binding
Cell(Cambridge,Mass.), 113, 2003
1OQY
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BU of 1oqy by Molmil
Structure of the DNA repair protein hHR23a
Descriptor: UV excision repair protein RAD23 homolog A
Authors:Walters, K.J, Lech, P.J, Goh, A.M, Wang, Q, Howley, P.M.
Deposit date:2003-03-11
Release date:2003-10-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a
Proc.Natl.Acad.Sci.USA, 100, 2003
3LDZ
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BU of 3ldz by Molmil
Crystal structure of human STAM1 VHS domain in complex with ubiquitin
Descriptor: Signal transducing adapter molecule 1, Ubiquitin
Authors:Ren, X, Hurley, J.H.
Deposit date:2010-01-13
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo.
Embo J., 29, 2010
3M63
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BU of 3m63 by Molmil
Crystal structure of Ufd2 in complex with the ubiquitin-like (UBL) domain of Dsk2
Descriptor: PENTAETHYLENE GLYCOL, POTASSIUM ION, Ubiquitin conjugation factor E4, ...
Authors:Haenzelmann, P, Schindelin, H.
Deposit date:2010-03-15
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain.
J.Biol.Chem., 285, 2010
3M62
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BU of 3m62 by Molmil
Crystal structure of Ufd2 in complex with the ubiquitin-like (UBL) domain of Rad23
Descriptor: PENTAETHYLENE GLYCOL, POTASSIUM ION, UV excision repair protein RAD23, ...
Authors:Haenzelmann, P, Schindelin, H.
Deposit date:2010-03-15
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain.
J.Biol.Chem., 285, 2010
3MHS
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BU of 3mhs by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
Authors:Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
Deposit date:2010-04-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
3MTN
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BU of 3mtn by Molmil
Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor
Descriptor: CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ...
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2010-04-30
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3N3K
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BU of 3n3k by Molmil
The catalytic domain of USP8 in complex with a USP8 specific inhibitor
Descriptor: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2010-05-20
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3NHE
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BU of 3nhe by Molmil
High Resolution Structure (1.26A) of USP2a in Complex with Ubiquitin
Descriptor: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION
Authors:Schormann, N, DeLucas, L.J, Powell McCombs, D.
Deposit date:2010-06-14
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:High resolution structure of USP2a in complex with ubiquitin
To be Published
3O65
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BU of 3o65 by Molmil
Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity
Descriptor: Putative ataxin-3-like protein, SODIUM ION, Ubiquitin
Authors:Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
Deposit date:2010-07-28
Release date:2010-11-24
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY.
J.Biol.Chem., 286, 2011
8JAR
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BU of 8jar by Molmil
Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-07
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JAL
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BU of 8jal by Molmil
Structure of CRL2APPBP2 bound with RxxGP degron (dimer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-06
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JAQ
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BU of 8jaq by Molmil
Structure of CRL2APPBP2 bound with RxxGP degron (tetramer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-06
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JAS
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BU of 8jas by Molmil
Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-07
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JAU
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BU of 8jau by Molmil
Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-07
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JAV
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BU of 8jav by Molmil
Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-07
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023

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