2ADU
| Human Methionine Aminopeptidase Complex with 4-Aryl-1,2,3-triazole Inhibitor | Descriptor: | 4-(3-METHYLPHENYL)-1H-1,2,3-TRIAZOLE, COBALT (II) ION, Methionine aminopeptidase 2 | Authors: | Kallander, L.S, Lu, Q, Chen, W, Tomaszek, T, Yang, G, Tew, D, Meek, T.D, Hofmann, G.A, Schulz-Pritchard, C.K, Smith, W.W, Janson, C.A, Ryan, M.D, Zhang, G.F, Johanson, K.O, Kirkpatrick, R.B, Ho, T.F, Fisher, P.W, Mattern, M.R, Johnson, R.K, Hansbury, M.J, Winkler, J.D, Ward, K.W, Veber, D.F, Thompson, S.K. | Deposit date: | 2005-07-20 | Release date: | 2005-09-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo J.Med.Chem., 48, 2005
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2ADV
| Crystal Structures Of Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism | Descriptor: | Glutaryl 7- Aminocephalosporanic Acid Acylase | Authors: | Kim, J.K, Yang, I.S, Shin, H.J, Cho, K.J, Ryu, E.K, Kim, S.H, Park, S.S, Kim, K.H. | Deposit date: | 2005-07-21 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.244 Å) | Cite: | Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries. Proc.Natl.Acad.Sci.USA, 103, 2006
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2ADW
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2ADX
| FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | THROMBOMODULIN | Authors: | Sampoli-Benitez, B.A, Hunter, M.J, Meininger, D.P, Komives, E.A. | Deposit date: | 1997-02-18 | Release date: | 1997-12-24 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern. J.Mol.Biol., 273, 1997
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2ADY
| Structural Basis of DNA Recognition by p53 Tetramers (complex IV) | Descriptor: | 5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION | Authors: | Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z. | Deposit date: | 2005-07-21 | Release date: | 2006-07-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis of DNA Recognition by p53 Tetramers Mol.Cell, 22, 2006
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2ADZ
| solution structure of the joined PH domain of alpha1-syntrophin | Descriptor: | Alpha-1-syntrophin | Authors: | Yan, J, Wen, W, Xu, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | Deposit date: | 2005-07-21 | Release date: | 2006-01-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin Embo J., 24, 2005
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2AE0
| Crystal structure of MltA from Escherichia coli reveals a unique lytic transglycosylase fold | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Membrane-bound lytic murein transglycosylase A | Authors: | Van Straaten, K.E, Dijkstra, B.W, Vollmer, W, Thunnissen, A.M.W.H. | Deposit date: | 2005-07-21 | Release date: | 2005-10-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of MltA from Escherichia coli Reveals a Unique Lytic Transglycosylase Fold J.Mol.Biol., 352, 2005
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2AE1
| TROPINONE REDUCTASE-II | Descriptor: | TROPINONE REDUCTASE-II | Authors: | Nakajima, K, Yamashita, A, Akama, H, Nakatsu, T, Kato, H, Hashimoto, T, Oda, J, Yamada, Y. | Deposit date: | 1997-10-27 | Release date: | 1998-11-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold. Proc.Natl.Acad.Sci.USA, 95, 1998
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2AE2
| TROPINONE REDUCTASE-II COMPLEXED WITH NADP+ AND PSEUDOTROPINE | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (TROPINONE REDUCTASE-II), PSEUDOTROPINE | Authors: | Yamashita, A, Kato, H, Wakatsuki, S, Tomizaki, T, Nakatsu, T, Nakajima, K, Hashimoto, T, Yamada, Y, Oda, J. | Deposit date: | 1999-01-26 | Release date: | 1999-02-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Biochemistry, 38, 1999
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2AE3
| Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism | Descriptor: | GLYCEROL, Glutaryl 7-Aminocephalosporanic Acid Acylase | Authors: | Kim, J.K, Yang, I.S, Shin, H.J, Cho, K.J, Ryu, E.K, Kim, S.H, Park, S.S, Kim, K.H. | Deposit date: | 2005-07-21 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries. Proc.Natl.Acad.Sci.USA, 103, 2006
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2AE4
| Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism | Descriptor: | GLYCEROL, Glutaryl 7-Aminocephalosporanic Acid Acylase, SULFATE ION | Authors: | Kim, J.K, Yang, I.S, Shin, H.J, Cho, K.J, Ryu, E.K, Kim, S.H, Park, S.S, Kim, K.H. | Deposit date: | 2005-07-21 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries. Proc.Natl.Acad.Sci.USA, 103, 2006
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2AE5
| Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism | Descriptor: | GLYCEROL, Glutaryl 7-Aminocephalosporanic Acid Acylase, SULFATE ION | Authors: | Kim, J.K, Yang, I.S, Shin, H.J, Cho, K.J, Ryu, E.K, Kim, S.H, Park, S.S, Kim, K.H. | Deposit date: | 2005-07-21 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries. Proc.Natl.Acad.Sci.USA, 103, 2006
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2AE6
| Crystal Structure of Acetyltransferase of GNAT family from Enterococcus faecalis V583 | Descriptor: | ETHANOL, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kim, Y, Hatzos, C, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-07-21 | Release date: | 2005-09-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal Structure of Acetyltransferase of GNAT family from Enterococcus faecalis V583 To be Published
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2AE7
| Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with Pentasaccharide | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, ... | Authors: | Ramasamy, V, Ramakrishnan, B, Boeggeman, E, Ratner, D.M, Seeberger, P.H, Qasba, P.K. | Deposit date: | 2005-07-21 | Release date: | 2005-10-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol., 353, 2005
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2AE8
| Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315 | Descriptor: | Imidazoleglycerol-phosphate dehydratase, MAGNESIUM ION | Authors: | Kim, Y, Quartey, P, Holzle, D, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-07-21 | Release date: | 2005-09-06 | Last modified: | 2015-05-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315 To be Published
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2AE9
| Solution Structure of the theta subunit of DNA polymerase III from E. coli | Descriptor: | DNA polymerase III, theta subunit | Authors: | Mueller, G.A, Kirby, T.W, Derose, E.F, Li, D, Schaaper, R.M, London, R.E. | Deposit date: | 2005-07-21 | Release date: | 2005-10-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nuclear Magnetic Resonance Solution Structure of the Escherichia coli DNA Polymerase III {theta} Subunit. J.Bacteriol., 187, 2005
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2AEB
| Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response. | Descriptor: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase 1, MANGANESE (II) ION | Authors: | Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W. | Deposit date: | 2005-07-21 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AEC
| Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with GlcNAc-beta1,2-Man-alpha1,6-Man-beta-OR | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose, ... | Authors: | Ramasamy, V, Ramakrishnan, B, Boeggeman, E, Ratner, D.M, Seeberger, P.H, Qasba, P.K. | Deposit date: | 2005-07-22 | Release date: | 2005-10-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol., 353, 2005
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2AEE
| Crystal structure of Orotate phosphoribosyltransferase from Streptococcus pyogenes | Descriptor: | CHLORIDE ION, GLYCEROL, Orotate phosphoribosyltransferase, ... | Authors: | Chang, C, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-07-22 | Release date: | 2005-09-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of Orotate phosphoribosyltransferase from Streptococcus pyogenes To be Published
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2AEF
| Crystal Structures of the MthK RCK Domain in Ca2+ bound form | Descriptor: | CALCIUM ION, Calcium-gated potassium channel mthK | Authors: | Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y. | Deposit date: | 2005-07-22 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability J.Biol.Chem., 280, 2005
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2AEG
| X-Ray Crystal Structure of Protein Atu5096 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR63. | Descriptor: | hypothetical protein AGR_pAT_140 | Authors: | Forouhar, F, Abashidze, M, Kuzin, A.P, Vorobiev, S.M, Shastry, R, Cooper, B, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-07-22 | Release date: | 2005-08-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of the Hypothetical Protein Atu5096 from Agrobacterium tumefaciens. To be Published
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2AEH
| Focal adhesion kinase 1 | Descriptor: | Focal adhesion kinase 1 | Authors: | Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J. | Deposit date: | 2005-07-22 | Release date: | 2005-10-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Crystal Structure of the FERM Domain of Focal Adhesion Kinase J.Biol.Chem., 281, 2006
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2AEI
| Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid | Descriptor: | 2-({6-{3-[AMINO(IMINO)METHYL]PHENOXY}-3,5-DIFLUORO-4-[(1-METHYL-3-PHENYLPROPYL)AMINO]-2-PYRIDINYL}OXY)BENZOIC ACID, CACODYLATE ION, CALCIUM ION, ... | Authors: | Adler, M, Whitlow, M. | Deposit date: | 2005-07-22 | Release date: | 2006-08-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex. Bioorg.Med.Chem.Lett., 15, 2005
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2AEJ
| Crystal Structures of the MthK RCK Domain in no Ca2+ bound form | Descriptor: | Calcium-gated potassium channel mthK | Authors: | Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y. | Deposit date: | 2005-07-22 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability J.Biol.Chem., 280, 2005
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2AEK
| R304K trichodiene synthase | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Trichodiene synthase | Authors: | Vedula, L.S, Cane, D.E, Christianson, D.W. | Deposit date: | 2005-07-22 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Role of arginine-304 in the diphosphate-triggered active site closure mechanism of trichodiene synthase. Biochemistry, 44, 2005
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