Crystal structure of MltA from Escherichia coli reveals a unique lytic transglycosylase fold

Summary for 2AE0

DescriptorMembrane-bound lytic murein transglycosylase A, 1,2-ETHANEDIOL, ACETIC ACID, ... (4 entities in total)
Functional Keywordsdouble-psi beta-barrel, small mixed parallel/antiparallel six stranded beta barrel, helical sub-domain, hydrolase
Biological sourceEscherichia coli
Cellular locationCell outer membrane; Lipid-anchor P0A935
Total number of polymer chains1
Total molecular weight38372.81
Van Straaten, K.E.,Dijkstra, B.W.,Vollmer, W.,Thunnissen, A.M.W.H. (deposition date: 2005-07-21, release date: 2005-10-04, Last modification date: 2017-10-11)
Primary citation
van Straaten, K.E.,Dijkstra, B.W.,Vollmer, W.,Thunnissen, A.M.W.H.
Crystal Structure of MltA from Escherichia coli Reveals a Unique Lytic Transglycosylase Fold
J.Mol.Biol., 352:1068-1080, 2005
PubMed: 16139297 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2005.07.067
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.239106.3%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report