2ADV

Crystal Structures Of Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism

Summary for 2ADV

• Entry DOI: 10.2210/pdb2adv/pdb
• Related: 2AE3 2AE4 2AE5
• Descriptor: Glutaryl 7- Aminocephalosporanic Acid Acylase, ... (4 entities in total)
• Functional Keywords: autoproteolysis, precursor activation, intermediate structure, cephalosporin acylase, hydrolase
• Biological source: Pseudomonas sp.; More
• Cellular location: Periplasm : P07662
• Total number of polymer chains: 3
• Total formula weight: 77342.73

Authors

Kim, J.K.,Yang, I.S.,Shin, H.J.,Cho, K.J.,Ryu, E.K.,Kim, S.H.,Park, S.S.,Kim, K.H. (deposition date: 2005-07-21, release date: 2006-01-24, Last modification date: 2024-03-13)

• Primary citation: Kim, J.K.,Yang, I.S.,Shin, H.J.,Cho, K.J.,Ryu, E.K.,Kim, S.H.,Park, S.S.,Kim, K.H.; Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries.; Proc.Natl.Acad.Sci.USA, 103:1732-1737, 2006; PubMed: 16446446; DOI: 10.1073/pnas.0507862103

Experimental method

X-RAY DIFFRACTION (2.244 Å)