2AEK

R304K trichodiene synthase

Summary for 2AEK

• Entry DOI: 10.2210/pdb2aek/pdb
• Related: 1JFA 1JFG 1KIY 1KIZ 1YJ4 1YYQ
• Descriptor: Trichodiene synthase, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: terpenoid cyclase fold, site-directed mutant, lyase
• Biological source: Fusarium sporotrichioides
• Total number of polymer chains: 2
• Total formula weight: 88342.05

Authors

Vedula, L.S.,Cane, D.E.,Christianson, D.W. (deposition date: 2005-07-22, release date: 2005-10-04, Last modification date: 2023-08-23)

• Primary citation: Vedula, L.S.,Cane, D.E.,Christianson, D.W.; Role of arginine-304 in the diphosphate-triggered active site closure mechanism of trichodiene synthase.; Biochemistry, 44:12719-12727, 2005; PubMed: 16171386; DOI: 10.1021/bi0510476

Experimental method

X-RAY DIFFRACTION (2.9 Å)