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2ADU

Human Methionine Aminopeptidase Complex with 4-Aryl-1,2,3-triazole Inhibitor

Summary for 2ADU
Entry DOI10.2210/pdb2adu/pdb
DescriptorMethionine aminopeptidase 2, COBALT (II) ION, 4-(3-METHYLPHENYL)-1H-1,2,3-TRIAZOLE, ... (4 entities in total)
Functional Keywordshydrolase, aminopeptidase, metal binding, protease
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P50579
Total number of polymer chains1
Total formula weight41647.06
Authors
Primary citationKallander, L.S.,Lu, Q.,Chen, W.,Tomaszek, T.,Yang, G.,Tew, D.,Meek, T.D.,Hofmann, G.A.,Schulz-Pritchard, C.K.,Smith, W.W.,Janson, C.A.,Ryan, M.D.,Zhang, G.F.,Johanson, K.O.,Kirkpatrick, R.B.,Ho, T.F.,Fisher, P.W.,Mattern, M.R.,Johnson, R.K.,Hansbury, M.J.,Winkler, J.D.,Ward, K.W.,Veber, D.F.,Thompson, S.K.
4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo
J.Med.Chem., 48:5644-5647, 2005
Cited by
PubMed: 16134930
DOI: 10.1021/jm050408c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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