2ADU
Human Methionine Aminopeptidase Complex with 4-Aryl-1,2,3-triazole Inhibitor
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CO A 501 |
| Chain | Residue |
| A | ASP251 |
| A | ASP262 |
| A | GLU459 |
| A | CO502 |
| A | R20906 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CO A 502 |
| Chain | Residue |
| A | CO501 |
| A | R20906 |
| A | ASP262 |
| A | HIS331 |
| A | GLU364 |
| A | GLU459 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE R20 A 906 |
| Chain | Residue |
| A | HIS231 |
| A | ASP251 |
| A | ASP262 |
| A | HIS331 |
| A | HIS339 |
| A | GLU364 |
| A | HIS382 |
| A | TYR444 |
| A | GLU459 |
| A | CO501 |
| A | CO502 |
| A | HOH671 |
Functional Information from PROSITE/UniProt
| site_id | PS01202 |
| Number of Residues | 17 |
| Details | MAP_2 Methionine aminopeptidase subfamily 2 signature. DIcKIDfGtHISGriiD |
| Chain | Residue | Details |
| A | ASP246-ASP262 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03175","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16540317","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03175","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14534293","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16134930","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16540317","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17350258","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17636946","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a16 |
| Chain | Residue | Details |
| A | LYS342 | |
| A | GLU364 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a16 |
| Chain | Residue | Details |
| A | GLU364 |
