1B2A
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![BU of 1b2a by Molmil](/molmil-images/mine/1b2a) | |
1B18
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1CPH
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![BU of 1cph by Molmil](/molmil-images/mine/1cph) | CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | Descriptor: | 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION | Authors: | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | Deposit date: | 1992-10-30 | Release date: | 1993-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
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1FUB
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![BU of 1fub by Molmil](/molmil-images/mine/1fub) | FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA | Descriptor: | CHLORIDE ION, INSULIN, A CHAIN, ... | Authors: | Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. | Deposit date: | 2000-09-14 | Release date: | 2000-10-16 | Last modified: | 2018-10-03 | Method: | POWDER DIFFRACTION | Cite: | The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
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1H02
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![BU of 1h02 by Molmil](/molmil-images/mine/1h02) | Human Insulin-like growth factor; SRS Daresbury data | Descriptor: | INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE | Authors: | Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. | Deposit date: | 2002-06-11 | Release date: | 2002-07-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
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1GUJ
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![BU of 1guj by Molmil](/molmil-images/mine/1guj) | Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation. | Descriptor: | INSULIN, SULFATE ION | Authors: | Whittingham, J.L, Scott, D.J, Chance, K, Wilson, A, Finch, J, Brange, J, Dodson, G.G. | Deposit date: | 2002-01-28 | Release date: | 2002-03-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Insulin at Ph2: Structural Analysis of the Conditions Promoting Insulin Fibre Formation J.Mol.Biol., 318, 2002
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1GZZ
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![BU of 1gzz by Molmil](/molmil-images/mine/1gzz) | Human Insulin-like growth factor; Hamburg data | Descriptor: | INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE | Authors: | Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. | Deposit date: | 2002-06-10 | Release date: | 2002-07-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
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1IGL
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![BU of 1igl by Molmil](/molmil-images/mine/1igl) | SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS | Descriptor: | INSULIN-LIKE GROWTH FACTOR II | Authors: | Torres, A.M, Forbes, B.E, Aplin, S.E, Wallace, J.C, Francis, G.L, Norton, R.S. | Deposit date: | 1994-12-29 | Release date: | 1995-02-14 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions. J.Mol.Biol., 248, 1995
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1GZR
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![BU of 1gzr by Molmil](/molmil-images/mine/1gzr) | Human Insulin-like growth factor; ESRF data | Descriptor: | INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE | Authors: | Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. | Deposit date: | 2002-05-28 | Release date: | 2002-07-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
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1GZY
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![BU of 1gzy by Molmil](/molmil-images/mine/1gzy) | Human Insulin-like growth factor; In-house data | Descriptor: | INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE | Authors: | Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. | Deposit date: | 2002-06-10 | Release date: | 2002-07-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
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1HIQ
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![BU of 1hiq by Molmil](/molmil-images/mine/1hiq) | |
1HIT
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1J73
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![BU of 1j73 by Molmil](/molmil-images/mine/1j73) | Crystal structure of an unstable insulin analog with native activity. | Descriptor: | ZINC ION, insulin a, insulin b | Authors: | Wan, Z, Zhao, M, Nakagawa, S, Jia, W, Weiss, M.A. | Deposit date: | 2001-05-15 | Release date: | 2001-05-30 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
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1IMX
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![BU of 1imx by Molmil](/molmil-images/mine/1imx) | 1.8 Angstrom crystal structure of IGF-1 | Descriptor: | BROMIDE ION, Insulin-like Growth Factor 1A, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE | Authors: | Vajdos, F.F, Ultsch, M, Schaffer, M.L, Deshayes, K.D, Liu, J, Skelton, N.J, de Vos, A.M. | Deposit date: | 2001-05-11 | Release date: | 2001-09-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions. Biochemistry, 40, 2001
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1HUI
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![BU of 1hui by Molmil](/molmil-images/mine/1hui) | INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES | Descriptor: | INSULIN | Authors: | Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. | Deposit date: | 1996-03-29 | Release date: | 1997-03-12 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Solution structure of an engineered insulin monomer at neutral pH. Biochemistry, 35, 1996
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1G7B
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![BU of 1g7b by Molmil](/molmil-images/mine/1g7b) | 1.3 A STRUCTURE OF T3R3 HUMAN INSULIN AT 100 K | Descriptor: | ACETONE, CHLORIDE ION, GLYCEROL, ... | Authors: | Smith, G.D, Pangborn, W.A, Blessing, R.H. | Deposit date: | 2000-11-09 | Release date: | 2001-08-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced? Acta Crystallogr.,Sect.D, 57, 2001
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1IZB
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1IOH
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![BU of 1ioh by Molmil](/molmil-images/mine/1ioh) | INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES | Descriptor: | PROTEIN (INSULIN PRECURSOR) | Authors: | Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. | Deposit date: | 1998-08-13 | Release date: | 1999-01-13 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix. J.Mol.Biol., 284, 1998
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1IOG
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![BU of 1iog by Molmil](/molmil-images/mine/1iog) | INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES | Descriptor: | PROTEIN (INSULIN PRECURSOR) | Authors: | Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. | Deposit date: | 1998-08-13 | Release date: | 1999-01-13 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix. J.Mol.Biol., 284, 1998
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1JCA
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![BU of 1jca by Molmil](/molmil-images/mine/1jca) | Non-standard Design of Unstable Insulin Analogues with Enhanced Activity | Descriptor: | ZINC ION, insulin a, insulin b | Authors: | Weiss, M.A, Wan, Z, Zhao, M, Chu, Y.-C, Nakagawa, S.H, Burke, G.T, Jia, W, Hellmich, R, Katsoyannis, P.G. | Deposit date: | 2001-06-08 | Release date: | 2001-06-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
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1HLS
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![BU of 1hls by Molmil](/molmil-images/mine/1hls) | NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16) | Descriptor: | INSULIN | Authors: | Ludvigsen, S, Kaarsholm, N.C. | Deposit date: | 1995-06-28 | Release date: | 1995-09-15 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr-->His, as determined by nuclear magnetic resonance spectroscopy. Biochemistry, 33, 1994
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1HO0
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![BU of 1ho0 by Molmil](/molmil-images/mine/1ho0) | NEW B-CHAIN MUTANT OF BOVINE INSULIN | Descriptor: | INSULIN | Authors: | Dupradeau, F.Y, Richard, T, Le Flem, G, Oulyadi, H, Prigent, Y, Monti, J.P. | Deposit date: | 2000-12-08 | Release date: | 2000-12-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A new B-chain mutant of insulin: comparison with the insulin crystal structure and role of sulfonate groups in the B-chain structure J.Pept.Res., 60, 2002
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1IZA
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1JCO
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![BU of 1jco by Molmil](/molmil-images/mine/1jco) | Solution structure of the monomeric [Thr(B27)->Pro,Pro(B28)->Thr] insulin mutant (PT insulin) | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Keller, D, Clausen, R, Josefsen, K, Led, J.J. | Deposit date: | 2001-06-11 | Release date: | 2001-10-03 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Flexibility and bioactivity of insulin: an NMR investigation of the solution structure and folding of an unusually flexible human insulin mutant with increased biological activity. Biochemistry, 40, 2001
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1FU2
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![BU of 1fu2 by Molmil](/molmil-images/mine/1fu2) | FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA | Descriptor: | CHLORIDE ION, INSULIN, A CHAIN, ... | Authors: | Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. | Deposit date: | 2000-09-13 | Release date: | 2000-10-16 | Last modified: | 2018-10-03 | Method: | POWDER DIFFRACTION | Cite: | The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
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