3WMS
| The crystal structure of Y195I mutant alpha-cyclodextrin glycosyltransferase from Paenibacillus macerans | Descriptor: | Alpha-cyclodextrin glucanotransferase, CALCIUM ION | Authors: | Xie, T, Hou, Y.J, Li, D.F, Yue, Y, Qian, S.J, Chao, Y.P. | Deposit date: | 2013-11-24 | Release date: | 2014-11-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of a mutant Y195I alpha-cyclodextrin glycosyltransferase with switched product specificity from alpha-cyclodextrin to beta-/ gamma-cyclodextrin J.Biotechnol., 182-183, 2014
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3WBB
| Crystal Structures of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum | Descriptor: | Diaminopimelate dehydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, W.D, Li, Z, Huang, C.H, Guo, R.T, Wu, Q.Q, Zhu, D.M. | Deposit date: | 2013-05-14 | Release date: | 2014-03-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum. Chembiochem, 15, 2014
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2A8S
| 2.45 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29, Manganese and GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, U8 snoRNA-binding protein X29 | Authors: | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | Deposit date: | 2005-07-08 | Release date: | 2006-03-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006
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8UA2
| Crystal Structure of infected cell protein 0 (ICP0) from herpes simplex virus 1 (proteolyzed fragment) | Descriptor: | IODIDE ION, RL2 | Authors: | Lovell, S, Kashipathy, M, Battaile, K.P, Cooper, A, Davido, D. | Deposit date: | 2023-09-20 | Release date: | 2024-02-28 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | HSV-1 ICP0 dimer domain adopts a novel beta-barrel fold. Proteins, 92, 2024
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3ZQ9
| Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 | Descriptor: | (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL, 1,2-ETHANEDIOL, CALCIUM ION, ... | Authors: | Ariza, A, Eklof, J.M, Spadiut, O, Offen, W.A, Roberts, S.M, Besenmatter, W, Friis, E.P, Skjot, M, Wilson, K.S, Brumer, H, Davies, G. | Deposit date: | 2011-06-08 | Release date: | 2011-06-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44. J.Biol.Chem., 286, 2011
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8DL4
| S. CEREVISIAE CYP51 COMPLEXED WITH Courmarin-containing INHIBITOR | Descriptor: | 7-(diethylamino)-N-[(2S)-2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]-2-oxo-2H-1-benzopyran-3-carboxamide, Lanosterol 14-alpha demethylase, PENTAETHYLENE GLYCOL, ... | Authors: | Ruma, Y.N, Keniya, M.V, Tyndall, J.D, Monk, B.C. | Deposit date: | 2022-07-06 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | S. CEREVISIAE CYP51 COMPLEXED WITH Courmarin-containing INHIBITOR To Be Published
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5XY4
| CATPO mutant - V536W | Descriptor: | CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase, ... | Authors: | Yuzugullu Karakus, Y, Goc, G, Balci, S, Pearson, A.R, Yorke, B. | Deposit date: | 2017-07-06 | Release date: | 2018-07-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase. Acta Crystallogr D Struct Biol, 74, 2018
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8JIG
| A Novel UHRF1-Targeted Compound | Descriptor: | E3 ubiquitin-protein ligase UHRF1, N-[2,4-bis(oxidanylidene)-1H-pyrimidin-5-yl]-N'-oxidanyl-octanediamide | Authors: | Chen, Y, Jiang, L. | Deposit date: | 2023-05-26 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Novel UHRF1-Targeted Compound To Be Published
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3OMC
| Structure of human SND1 extended tudor domain in complex with the symmetrically dimethylated arginine PIWIL1 peptide R4me2s | Descriptor: | CHLORIDE ION, SYNTHETIC PEPTIDE, Staphylococcal nuclease domain-containing protein 1 | Authors: | Lam, R, Liu, K, Guo, Y.H, Bian, C.B, Xu, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2010-08-26 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain. Proc.Natl.Acad.Sci.USA, 107, 2010
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3ZFX
| Crystal structure of EphB1 | Descriptor: | EPHRIN TYPE-B RECEPTOR 1, SULFATE ION | Authors: | Debreczeni, J.E, Overman, R, Truman, C, McAlister, M, Attwood, T.K. | Deposit date: | 2012-12-12 | Release date: | 2014-01-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Completing the Structural Family Portrait of the Human Ephb Tyrosine Kinase Domains Protein Sci., 23, 2014
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7Y1H
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | 1-(5-chloranyl-4-methyl-benzimidazol-1-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-08 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y1W
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | (2R,3S)-2-[3-[4,5-bis(chloranyl)benzimidazol-1-yl]propyl]piperidin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-09 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y28
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | 1-[6-(3-fluorophenyl)benzimidazol-1-yl]-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-09 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7XV7
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7Y3S
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | Descriptor: | 1-(6-bromanyl-7-methyl-imidazo[4,5-b]pyridin-3-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | Deposit date: | 2022-06-12 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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1AND
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5WPT
| Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | Deposit date: | 2017-08-07 | Release date: | 2017-10-18 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs. Nature, 550, 2017
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3OO4
| R-state human hemoglobin: nitriheme modified at alpha | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, NITRITE ION, ... | Authors: | Yi, J, Thormas, L.M, Richter-Addo, G.B. | Deposit date: | 2010-08-30 | Release date: | 2011-09-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic Trapping of Heme Loss Intermediates during the Nitrite-Induced Degradation of Human Hemoglobin. Biochemistry, 50, 2011
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1L7M
| HIGH RESOLUTION LIGANDED STRUCTURE OF PHOSPHOSERINE PHOSPHATASE (PI COMPLEX) | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, Phosphoserine Phosphatase | Authors: | Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2002-03-15 | Release date: | 2002-04-03 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states. J.Mol.Biol., 319, 2002
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8GQE
| Crystal structure of the W285A mutant of UVR8 in complex with RUP2 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ultraviolet-B receptor UVR8, WD repeat-containing protein RUP2 | Authors: | Wang, Y.D, Wang, L.X, Guan, Z.Y, chang, H.F, Yin, P. | Deposit date: | 2022-08-30 | Release date: | 2022-09-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | RUP2 facilitates UVR8 redimerization via two interfaces. Plant Commun., 4, 2023
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6UW2
| Clotrimazole bound complex of Acanthamoeba castellanii CYP51 | Descriptor: | 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, GUANIDINE, Obtusifoliol 14alphademethylase, ... | Authors: | Sharma, V, Podust, L.M. | Deposit date: | 2019-11-04 | Release date: | 2020-10-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Domain-Swap Dimerization of Acanthamoeba castellanii CYP51 and a Unique Mechanism of Inactivation by Isavuconazole. Mol.Pharmacol., 98, 2020
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3ZCH
| Ascorbate peroxidase W41A-H42M mutant | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ASCORBATE PEROXIDASE, POTASSIUM ION, ... | Authors: | Gumiero, A, Raven, E.L, Moody, P.C.E. | Deposit date: | 2012-11-20 | Release date: | 2012-12-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Probing the Conformational Mobility of the Active Site of Ascorbate Peroxidase Dalton Trans, 42, 2013
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7DB7
| Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound GDI05-001 | Descriptor: | 1-[3-[2-(1H-indol-3-yl)ethylsulfamoyl]phenyl]-3-(1,3-thiazol-2-yl)urea, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, ... | Authors: | Xu, M, Zhang, X, Xu, L, Chen, S. | Deposit date: | 2020-10-19 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis . J.Biol.Chem., 2021
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8DWT
| SPOP W22R Form 2 | Descriptor: | Speckle-type POZ protein | Authors: | Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H. | Deposit date: | 2022-08-02 | Release date: | 2023-01-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Mol.Cell, 83, 2023
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8DWV
| Full-length wild type SPOP | Descriptor: | Speckle-type POZ protein | Authors: | Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H. | Deposit date: | 2022-08-02 | Release date: | 2023-01-18 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Mol.Cell, 83, 2023
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