PDB: 98078 resultsInfo pagesStatus searchChemie searchBIRD

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4Q87	Crystal structure of 1-hydroxy-4-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II Descriptor: 1-hydroxy-4-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Martin, D.P, Cohen, S.M. Deposit date: 2014-04-25 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57, 2014
4Q8Y	Crystal structure of 2-hydroxyisoquinoline-1(2H)-thione bound to human carbonic anhydrase II Descriptor: 2-hydroxyisoquinoline-1(2H)-thione, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... Authors: Martin, D.P, Cohen, S.M. Deposit date: 2014-04-28 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57, 2014
5YNW	Crystal structure of an aromatic prenyltransferase FAMD1 from Fischerella ambigua UTEX 1903 in complex with DMASPP and INN Descriptor: 3-[(Z)-2-isocyanoethenyl]-1H-indole, DIMETHYLALLYL S-THIOLODIPHOSPHATE, GLYCEROL, ... Authors: Wang, J, Liu, W.D, Chen, C.C, Guo, R.T. Deposit date: 2017-10-25 Release date: 2018-08-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural insight into a novel indole prenyltransferase in hapalindole-type alkaloid biosynthesis. Biochem. Biophys. Res. Commun., 495, 2018
4PZ5	Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of BBK32 from Borrelia burgdorferi Descriptor: Fibronectin, Fibronectin-binding protein BBK32 Authors: Harris, G, Potts, J.R. Deposit date: 2014-03-28 Release date: 2014-07-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Borrelia burgdorferi Protein BBK32 Binds to Soluble Fibronectin via the N-terminal 70-kDa Region, Causing Fibronectin to Undergo Conformational Extension. J.Biol.Chem., 289, 2014
4XAI	Crystal Structure of red flour beetle NR2E1/TLX Descriptor: Grunge, isoform J, Maltose-binding periplasmic protein,Tailless ortholog, ... Authors: Zhi, X, Zhou, E, Xu, E. Deposit date: 2014-12-14 Release date: 2015-03-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for corepressor assembly by the orphan nuclear receptor TLX. Genes Dev., 29, 2015
4Q7V	Crystal structure of 1-hydroxy-5-methylpyridine-2(1H)-thione bound to human carbonic anhydrase II Descriptor: 1-hydroxy-5-methylpyridine-2(1H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Martin, D.P, Cohen, S.M. Deposit date: 2014-04-25 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57, 2014
4Q83	Crystal structure of 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II Descriptor: 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... Authors: Martin, D.P, Cohen, S.M. Deposit date: 2014-04-25 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57, 2014
8P8M	Yeast 60S ribosomal subunit, RPL39 deletion Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. Deposit date: 2023-06-01 Release date: 2024-06-12 Last modified: 2024-12-25 Method: ELECTRON MICROSCOPY (2.66 Å) Cite: Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of a subset of proteins with alpha helical domains. Nucleic Acids Res., 52, 2024
4Q8X	Crystal structure of 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II Descriptor: 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Martin, D.P, Cohen, S.M. Deposit date: 2014-04-28 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57, 2014
8PFR	Mouse RPL39L integrated into the yeast 60S ribosomal subunit Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. Deposit date: 2023-06-16 Release date: 2024-06-26 Last modified: 2024-12-25 Method: ELECTRON MICROSCOPY (2.15 Å) Cite: Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of a subset of proteins with alpha helical domains. Nucleic Acids Res., 52, 2024
4Q99	Crystal structure of 2-mercapto-4-methylphenol bound to human carbonic anhydrase II Descriptor: 4-methyl-2-sulfanylphenol, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Martin, D.P, Cohen, S.M. Deposit date: 2014-04-29 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57, 2014
8P8U	Yeast 60S ribosomal subunit Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. Deposit date: 2023-06-02 Release date: 2024-06-12 Last modified: 2024-12-25 Method: ELECTRON MICROSCOPY (2.23 Å) Cite: Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of a subset of proteins with alpha helical domains. Nucleic Acids Res., 52, 2024
8P8N	Mouse RPL39 integrated into the yeast 60S ribosomal subunit Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. Deposit date: 2023-06-02 Release date: 2024-06-12 Last modified: 2024-12-25 Method: ELECTRON MICROSCOPY (2.15 Å) Cite: Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of a subset of proteins with alpha helical domains. Nucleic Acids Res., 52, 2024
6FNC	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ... Authors: Bier, D, Ottann, C. Deposit date: 2018-02-02 Release date: 2018-07-04 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
3KW0	Crystal structure of Cysteine peptidase (NP_982244.1) from BACILLUS CEREUS ATCC 10987 at 2.50 A resolution Descriptor: CHLORIDE ION, Cysteine peptidase, LYSINE Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2009-11-30 Release date: 2009-12-15 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites. Plos One, 6, 2011
8Y4Z	Monomeric HERC5 HECT c-lobe structure in solution Descriptor: E3 ISG15--protein ligase HERC5 Authors: Dag, C, Lambert, M, Kahraman, K, Lohn, F, Lee, W, Gocenler, O, Guntert, P, Dotsch, V. Deposit date: 2024-01-31 Release date: 2024-02-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Monomeric HERC5 HECT c-lobe structure in solution To Be Published
6FN9	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ... Authors: Bier, D, Ottmann, C. Deposit date: 2018-02-02 Release date: 2018-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
3HPI	Crystal structure of maltose-binding protein mutant with bound sucrose Descriptor: ACETATE ION, Maltose-binding periplasmic protein, ZINC ION, ... Authors: Gould, A.D, Shilton, B.H. Deposit date: 2009-06-04 Release date: 2010-02-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Studies of the maltose transport system reveal a mechanism for coupling ATP hydrolysis to substrate translocation without direct recognition of substrate. J.Biol.Chem., 285, 2010
7SCQ	tRNA-like Structure from Brome Mosaic Virus Bound to Tyrosyl-tRNA Synthetase from Phaseolus vulgaris. Conformation: Bound State 2. Descriptor: Tyrosine--tRNA ligase, tRNA-like structure from brome mosaic virus RNA 3. Authors: Kieft, J.S, Bonilla, S.L. Deposit date: 2021-09-28 Release date: 2021-12-01 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (6 Å) Cite: A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure. Science, 374, 2021
7SC6	tRNA-like Structure from Brome Mosaic Virus Bound to Tyrosyl-tRNA Synthetase from Phaseolus vulgaris. Conformation: Bound State 1. Descriptor: Tyrosine--tRNA ligase, tRNA-like structure from brome mosaic virus RNA 3 Authors: Kieft, J.S, Bonilla, S.L. Deposit date: 2021-09-27 Release date: 2021-12-01 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (5.51 Å) Cite: A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure. Science, 374, 2021
6IY6	Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS) Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Aspartate--tRNA ligase, cytoplasmic, ... Authors: Park, S.H, Hahn, H, Han, B.W. Deposit date: 2018-12-13 Release date: 2019-09-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.6 Å) Cite: The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex. Iucrj, 6, 2019
3I5D	Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor Authors: Kawate, T, Michel, J.C, Gouaux, E. Deposit date: 2009-07-05 Release date: 2009-08-04 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (3.46 Å) Cite: Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature, 460, 2009
3DKS	DsbA substrate complex Descriptor: Thiol:disulfide interchange protein dsbA, siga peptide Authors: Paxman, J.J, Borg, N.A, Horne, J, Rossjohn, J, Thompson, P.E, Piek, S, Kahler, C.M, Sakellaris, H, Scanlon, M.J. Deposit date: 2008-06-25 Release date: 2009-05-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes J.Biol.Chem., 284, 2009
6PRF	HIV-1 Protease multiple drug resistant clinical isolate mutant PR20 with GRL-14213A Descriptor: (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, Protease, YTTRIUM ION Authors: Kneller, D.W, Agniswamy, J, Weber, I.T. Deposit date: 2019-07-10 Release date: 2019-09-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.21 Å) Cite: Potent antiviral HIV-1 protease inhibitor combats highly drug resistant mutant PR20. Biochem.Biophys.Res.Commun., 519, 2019
3DN5	Aldose Reductase in complex with novel biarylic inhibitor Descriptor: 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Steuber, H, Klebe, G. Deposit date: 2008-07-01 Release date: 2009-04-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structure-Based Optimization of Aldose Reductase Inhibitors Originating from Virtual Screening Chemmedchem, 4, 2009

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