4Q87

Crystal structure of 1-hydroxy-4-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II

Summary for 4Q87

Entry DOI	10.2210/pdb4q87/pdb
Related	3M1K 4Q7P 4Q7S 4Q7V 4Q7W 4Q81 4Q83 4Q8X 4Q8Y 4Q8Z 4Q90 4Q99 4Q9Y
Descriptor	Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (6 entities in total)
Functional Keywords	lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29949.47
Authors	Martin, D.P.,Cohen, S.M. (deposition date: 2014-04-25, release date: 2015-03-11, Last modification date: 2023-09-20)
Primary citation	Martin, D.P.,Blachly, P.G.,McCammon, J.A.,Cohen, S.M. Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57:7126-7135, 2014 Cited by PubMed: 25116076 DOI: 10.1021/jm500984b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation