PDB: 9760 resultsInfo pagesStatus searchChemie searchBIRD

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7V0P	Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a potently neutralizing human antibody IgG-106 Descriptor: IgG 106 Fab heavy chain, IgG 106 Fab light chain, Spike glycoprotein E1, ... Authors: Bandyopadhyay, A, Klose, T, Kuhn, R.J. Deposit date: 2022-05-10 Release date: 2023-04-05 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120, 2023
7TGF	Single-domain VHH intrabodies neutralize ricin toxin. Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin chain A, ... Authors: Rudolph, M.J, Mantis, N. Deposit date: 2022-01-07 Release date: 2022-10-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.347 Å) Cite: Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
7K22	Murine polyomavirus pentavalent capsomer with 8A7H5 Fab, subparticle reconstruction Descriptor: 8A7H5 Fab heavy chain, 8A7H5 Fab light chain, Capsid protein VP1 Authors: Goetschius, D.J, Hafenstein, S.L. Deposit date: 2020-09-08 Release date: 2020-10-07 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7K23	Murine polyomavirus hexavalent capsomer with 8A7H5 Fab, subparticle reconstruction Descriptor: 8A7H5 Fab heavy chain, 8A7H5 Fab light chain, Capsid protein VP1 Authors: Goetschius, D.J, Hafenstein, S.L. Deposit date: 2020-09-08 Release date: 2020-10-07 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7K25	Murine polyomavirus hexavalent capsomer, subparticle reconstruction Descriptor: Capsid protein VP1 Authors: Goetschius, D.J, Hafenstein, S.L. Deposit date: 2020-09-08 Release date: 2020-10-07 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7K24	Murine polyomavirus pentavalent capsomer, subparticle reconstruction Descriptor: Capsid protein VP1 Authors: Goetschius, D.J, Hafenstein, S.L. Deposit date: 2020-09-08 Release date: 2020-10-07 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7MXE	Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ... Authors: Abernathy, M.E, Bjorkman, P.J. Deposit date: 2021-05-19 Release date: 2021-10-27 Last modified: 2021-11-03 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope. Npj Vaccines, 6, 2021
5J57	V5E1-RTA complex Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... Authors: Rudolph, M.J. Deposit date: 2016-04-01 Release date: 2016-12-07 Last modified: 2019-12-11 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
7ZWF	Pfs48/45 bound to scFv fragment of monoclonal antibody 32F3 Descriptor: 32F3scFv, Gametocyte surface protein P45/48, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Ko, K.T, Lennartz, F.L, Higgins, M.K. Deposit date: 2022-05-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.132 Å) Cite: Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies. Nat Commun, 13, 2022
8E1G	SARS-CoV-2 RBD in complex with Omicron-neutralizing antibody 2A10 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A10 Fab, heavy chain, ... Authors: Wasserman, H, Hastie, K.M, Buck, T.K, Saphire, E.O. Deposit date: 2022-08-10 Release date: 2023-06-28 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence. Cell Rep, 42, 2023
5TP3	Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4 Descriptor: F-VHH-4 Authors: Wrapp, D, Gilman, M.S.A, McLellan, J.S. Deposit date: 2016-10-19 Release date: 2017-02-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.874 Å) Cite: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
6CDE	Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ... Authors: Acharya, P, Xu, K, Liu, K, Carragher, B, Potter, C.S, Kwong, P.D. Deposit date: 2018-02-08 Release date: 2018-05-16 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018
7D3L	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY F145 Descriptor: F145 VH, F145 VL, O/TIBET/99 VP1, ... Authors: He, Y, Lou, Z. Deposit date: 2020-09-19 Release date: 2021-04-14 Last modified: 2021-05-12 Method: ELECTRON MICROSCOPY (3.68 Å) Cite: Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
6XRJ	Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage Descriptor: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment Authors: Manne, K, Nicely, N.I, Acharya, P. Deposit date: 2020-07-13 Release date: 2020-12-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
5E1H	Ricin toxin in complex with neutralizing single chain monoclonal antibodies (VHHs) Descriptor: CHLORIDE ION, F8(JOB10) VHH antibody, Ricin Authors: Rudolph, M.J, Vance, D, Shoemaker, C, Mantis, N. Deposit date: 2015-09-29 Release date: 2016-08-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.032 Å) Cite: Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit. Proteins, 84, 2016
7D3M	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY R50 Descriptor: O/TIBET/99 VP1, O/TIBET/99 VP2, O/TIBET/99 VP3, ... Authors: He, Y, Lou, Z. Deposit date: 2020-09-19 Release date: 2021-04-14 Last modified: 2021-05-12 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
7D3K	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY B77 Descriptor: B77 VH, B77 VL, O/TIBET/99 VP1, ... Authors: He, Y, Lou, Z. Deposit date: 2020-09-19 Release date: 2021-04-14 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
8F0I	Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody COVA309-22 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA309-22 heavy chain, COVA309-22 light chain, ... Authors: Yuan, M, Wilson, I.A. Deposit date: 2022-11-03 Release date: 2023-09-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual. Iscience, 26, 2023
7MEP	BG505 SOSIP.v5.2(7S) in complex with the monoclonal antibodies Rh.33172 mAb.1 and RM19R Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2(7S) - gp120, ... Authors: Antanasijevic, A, Ward, A.B. Deposit date: 2021-04-07 Release date: 2022-01-26 Last modified: 2022-08-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7M30	Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25 Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain, 1-32 Fab Heavy Chain, ... Authors: Wrapp, D, McLellan, J.S. Deposit date: 2021-03-17 Release date: 2021-08-11 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.81 Å) Cite: Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
4HFW	Anti Rotavirus Antibody Descriptor: 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION Authors: Spiller, B.W, Aiyegbo, M, Crowe, J.E. Deposit date: 2012-10-05 Release date: 2013-05-29 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore. Plos One, 8, 2013
7LM8	Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with two cross-neutralizing antibodies CV38-142 and COVA1-16 Fabs isolated from COVID-19 patients Descriptor: 1,2-ETHANEDIOL, COVA1-16 Fab heavy chain, COVA1-16 Fab light chain, ... Authors: Liu, H, Wilson, I.A. Deposit date: 2021-02-05 Release date: 2021-03-31 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.936 Å) Cite: A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host Microbe, 29, 2021
8CZ8	Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics Descriptor: Mesothelin, cleaved form, SULFATE ION, ... Authors: Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. Deposit date: 2022-05-24 Release date: 2023-06-07 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
8SGU	Crystal structure of the SARS-CoV-2 receptor binding domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... Authors: Sankhala, R.S, Jensen, J.L, Joyce, M.G. Deposit date: 2023-04-13 Release date: 2023-12-13 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure, 32, 2024
6CDI	Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ... Authors: Acharya, P, Xu, K, Liu, K, Carragher, B, Potter, C.S, Kwong, P.D. Deposit date: 2018-02-08 Release date: 2018-05-16 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

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