PDB: 2718 resultsInfo pagesStatus searchChemie searchBIRD

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8FC4	Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.45A resolution Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... Authors: Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. Deposit date: 2022-12-01 Release date: 2023-07-26 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FL6	Human nuclear pre-60S ribosomal subunit (State J1) Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Vanden Broeck, A, Klinge, S. Deposit date: 2022-12-21 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: Principles of human pre-60 S biogenesis. Science, 381, 2023
8GZU	Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2 Descriptor: 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ... Authors: Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. Deposit date: 2022-09-27 Release date: 2023-06-14 Method: ELECTRON MICROSCOPY (4.18 Å) Cite: Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
8GYM	Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2 Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... Authors: Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. Deposit date: 2022-09-23 Release date: 2023-06-14 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
7Y41	Mycobacterium smegmatis 50S ribosomal subunit from Log Phase of growth Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... Authors: Sengupta, J, Baid, P. Deposit date: 2022-06-13 Release date: 2023-05-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Cryo-EM captures a unique conformational rearrangement in 23S rRNA helices of the Mycobacterium 50S subunit. Int.J.Biol.Macromol., 253, 2023
8G6W	Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe Descriptor: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ... Authors: Majumdar, C, Cate, J.H.D. Deposit date: 2023-02-16 Release date: 2023-04-05 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.02 Å) Cite: Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome. Acs Cent.Sci., 9, 2023
8G6X	Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe Descriptor: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminobenzamide, ... Authors: Majumdar, C, Cate, J.H.D. Deposit date: 2023-02-16 Release date: 2023-03-22 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.31 Å) Cite: Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome. Acs Cent.Sci., 9, 2023
8G6Y	Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site 3-aminopyridine-4-carboxylic acid charged NH-tRNAPhe Descriptor: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminopyridine-4-carboxamide, ... Authors: Majumdar, C, Cate, J.H.D. Deposit date: 2023-02-16 Release date: 2023-04-05 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.09 Å) Cite: Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome. Acs Cent.Sci., 9, 2023
8GLP	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. Deposit date: 2023-03-22 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (1.67 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G7Q	Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
8G7R	Structure of the Escherichia coli 70S ribosome in complex with A-site tRNAIle(LAU) bound to the cognate AUA codon (Structure III) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
8G7P	Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the cognate AUA codon (Structure I) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
8G7S	Structure of the Escherichia coli 70S ribosome in complex with P-site tRNAIle(LAU) bound to the cognate AUA codon (Structure IV) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 31, 2024
8HKY	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-08-30 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4.45 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HKZ	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16S rRNA (1493-MER), 23S rRNA (2996-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-08-30 Last modified: 2023-10-11 Method: ELECTRON MICROSCOPY (4.78 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HKU	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 23s rRNA (2996-MER), 50S ribosomal protein L1, 50S ribosomal protein L10e, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-08-16 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.72 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HKV	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 23s rRNA (2996-MER), 50S ribosomal protein L10e, 50S ribosomal protein L13, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-08-16 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4.94 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
7XNY	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Cheng, J, Beckmann, R. Deposit date: 2022-04-30 Release date: 2023-04-05 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer Discov, 13, 2023
8FIZ	Cryo-EM structure of E. coli 70S Ribosome containing mRNA and tRNA (in the transcription-translation complex) Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. Deposit date: 2022-12-18 Release date: 2023-03-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
8FON	Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. Deposit date: 2023-01-02 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.64 Å) Cite: Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches. J.Biol.Chem., 299, 2023
8HL2	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-09-20 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HL3	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-09-20 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HL5	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16S rRNA (1493-MER), 23S rRNA (2991-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-10-04 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (5.72 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
7W4N	Deactive state CI from Q1-NADH dataset, Subclass 5 Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J, Yang, M. Deposit date: 2021-11-28 Release date: 2023-01-25 Last modified: 2023-06-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
7W4F	Active state CI from Q1-NADH dataset, Subclass 4 Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Gu, J, Yang, M. Deposit date: 2021-11-27 Release date: 2023-01-25 Last modified: 2023-06-28 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022

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