PDB: 387 resultsInfo pagesStatus searchChemie searchBIRD

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7CAX	Crystal structure of bacterial reductase Descriptor: 1,2-ETHANEDIOL, 3-oxoacyl-ACP reductase FabG, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Kim, Y, Lee, W.C. Deposit date: 2020-06-10 Release date: 2021-06-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.846 Å) Cite: Crystal structure of bacterial reductase To be published
7DZT	Cyrstal structure of PETase from Rhizobacter gummiphilus Descriptor: DLH domain-containing protein Authors: Sagong, H.-Y, Kim, K.-J. Deposit date: 2021-01-26 Release date: 2021-07-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Implications for the PET decomposition mechanism through similarity and dissimilarity between PETases from Rhizobacter gummiphilus and Ideonella sakaiensis. J Hazard Mater, 416, 2021
7DZV	Cyrstal structure of PETase E186A mutant from Rhizobacter gummiphilus Descriptor: DLH domain-containing protein, GLYCEROL Authors: Sagong, H.-Y, Kim, K.-J. Deposit date: 2021-01-26 Release date: 2021-07-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Implications for the PET decomposition mechanism through similarity and dissimilarity between PETases from Rhizobacter gummiphilus and Ideonella sakaiensis. J Hazard Mater, 416, 2021
7DZU	Cyrstal structure of PETase K169A mutant from Rhizobacter gummiphilus Descriptor: DLH domain-containing protein Authors: Sagong, H.-Y, Kim, K.-J. Deposit date: 2021-01-26 Release date: 2021-07-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Implications for the PET decomposition mechanism through similarity and dissimilarity between PETases from Rhizobacter gummiphilus and Ideonella sakaiensis. J Hazard Mater, 416, 2021
1BKD	COMPLEX OF HUMAN H-RAS WITH HUMAN SOS-1 Descriptor: H-RAS, SON OF SEVENLESS-1 Authors: Boriack-Sjodin, P.A, Margarit, S.M, Sagi, D.B, Kuriyan, J. Deposit date: 1998-07-06 Release date: 1999-01-13 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The structural basis of the activation of Ras by Sos. Nature, 394, 1998
6AIX	Crystal structure of DXO in complex with adenosine 3', 5' bisphosphate and two magnesium ions Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Decapping and exoribonuclease protein, MAGNESIUM ION Authors: Chang, J.H, Tong, L. Deposit date: 2018-08-25 Release date: 2018-10-17 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate. Biochem. Biophys. Res. Commun., 504, 2018
6AIY	Crystal structure of DXO (E234A mutant) in complex with adenosine 3', 5' bisphosphate and two magnesium ions Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Decapping and exoribonuclease protein, MAGNESIUM ION Authors: Chang, J.H, Tong, L. Deposit date: 2018-08-25 Release date: 2018-10-17 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.902 Å) Cite: Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate. Biochem. Biophys. Res. Commun., 504, 2018
6AKV	Crystal structure of LysB4, the endolysin from Bacillus cereus-targeting bacteriophage B4 Descriptor: CHLORIDE ION, LysB4, SULFATE ION, ... Authors: Hong, S, Ha, N.-C. Deposit date: 2018-09-03 Release date: 2019-02-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure of LysB4, an Endolysin fromBacillus cereus-Targeting Bacteriophage B4. Mol. Cells, 42, 2019
6BVL	Ras:SOS:Ras in complex with a small molecule activator Descriptor: FORMIC ACID, GLYCEROL, GTPase HRAS, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2017-12-13 Release date: 2018-10-24 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.748 Å) Cite: Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
6BVJ	Ras:SOS:Ras in complex with a small molecule activator Descriptor: 5-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, FORMIC ACID, GLYCEROL, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2017-12-13 Release date: 2018-10-24 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.747 Å) Cite: Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
6BVM	Ras:SOS:Ras in complex with a small molecule activator Descriptor: (2S)-2-amino-1-[(3aR,6aS)-5-[(5-chloro-1H-indol-3-yl)methyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-3-(1H-indol-3-yl)propan-1-one, FORMIC ACID, GLYCEROL, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2017-12-13 Release date: 2018-10-24 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.796 Å) Cite: Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
6BVI	Ras:SOS:Ras in complex with a small molecule activator Descriptor: 6-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, FORMIC ACID, GLYCEROL, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2017-12-13 Release date: 2018-10-24 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.746 Å) Cite: Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
6CUP	Ras:SOS:Ras in complex with a small molecule activator Descriptor: FORMIC ACID, GLYCEROL, GTPase HRas, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2018-03-26 Release date: 2019-02-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.833 Å) Cite: Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. ACS Med Chem Lett, 9, 2018
6CUR	Ras:SOS:Ras in complex with a small molecule activator Descriptor: FORMIC ACID, GLYCEROL, GTPase HRas, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2018-03-26 Release date: 2019-02-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. ACS Med Chem Lett, 9, 2018
6CUO	Ras:SOS:Ras in complex with a small molecule activator Descriptor: FORMIC ACID, GLYCEROL, GTPase HRas, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2018-03-26 Release date: 2019-02-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. ACS Med Chem Lett, 9, 2018
6D37	Trp-cage tr16b R16Nva : Elimination of pH Dependent Interactions Descriptor: ALA-TYR-ALA-GLN-TRP-LEU-ALA-ASP-DAL-GLY-PRO-ALA-SER-DAL-NVA-PRO-PRO-PRO-SER Authors: Byrne, A, Andersen, N.H. Deposit date: 2018-04-14 Release date: 2019-03-13 Last modified: 2019-12-04 Method: SOLUTION NMR Cite: Reversing the typical pH stability profile of the Trp-cage. Biopolymers, 110, 2019
6D8E	Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor Descriptor: (4-fluorophenyl)methyl {2-[(1-methyl-1H-pyrazol-3-yl)amino]pyrimidin-4-yl}[3-(propanoylamino)phenyl]carbamate, Epidermal growth factor receptor Authors: Park, E, Eck, M.J. Deposit date: 2018-04-26 Release date: 2018-07-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.537 Å) Cite: Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor. Angew. Chem. Int. Ed. Engl., 57, 2018
6IQ6	Crystal structure of GAPDH Descriptor: (2Z)-4-methoxy-4-oxobut-2-enoic acid, Glyceraldehyde-3-phosphate dehydrogenase Authors: Park, J.B, Park, H.Y. Deposit date: 2018-11-06 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural Study of Monomethyl Fumarate-Bound Human GAPDH. Mol.Cells, 42, 2019
6ICI	Crystal structure of human MICAL3 Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3 Authors: Hwang, K.Y, Kim, J.S. Deposit date: 2018-09-06 Release date: 2020-03-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3. Iucrj, 7, 2020
6JJL	Crystal structure of the DegP dodecamer with a modulator Descriptor: CYS-TYR-ARG-LYS-LEU, Periplasmic serine endoprotease DegP Authors: Cho, H, Choi, Y, Lee, H.H, Kim, S. Deposit date: 2019-02-26 Release date: 2020-09-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy. Commun Biol, 3, 2020
6JJK	Crystal structure of the DegP dodecamer with a modulator Descriptor: CYS-TYR-TYR-LYS-ILE, Periplasmic serine endoprotease DegP Authors: Cho, H, Choi, Y, Lee, H.H, Kim, S. Deposit date: 2019-02-26 Release date: 2020-09-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy Commun Biol, 3, 2020
6JJO	Crystal structure of the DegP dodecamer with a modulator Descriptor: Periplasmic serine endoprotease DegP, TMB-CYRKL modulator Authors: Cho, H, Choi, Y, Lee, H.H, Kim, S. Deposit date: 2019-02-26 Release date: 2020-09-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.157 Å) Cite: Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy Commun Biol, 3, 2020
6JTT	MHETase in complex with BHET Descriptor: 4-(2-hydroxyethyloxycarbonyl)benzoic acid, CALCIUM ION, Mono(2-hydroxyethyl) terephthalate hydrolase, ... Authors: Sagong, H.-Y, Seo, H, Kim, K.-J. Deposit date: 2019-04-12 Release date: 2020-04-15 Last modified: 2020-10-28 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Decomposition of PET film by MHETase using Exo-PETase function Acs Catalysis, 10, 2020
6JTU	Crystal structure of MHETase from Ideonella sakaiensis Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... Authors: Sagong, H.-Y, Seo, H, Kim, K.-J. Deposit date: 2019-04-12 Release date: 2020-04-15 Last modified: 2020-10-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Decomposition of PET film by MHETase using Exo-PETase function Acs Catalysis, 10, 2020
6KX8	Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound Descriptor: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2 Authors: Miller, S.A, Aikawa, Y, Hirota, T. Deposit date: 2019-09-10 Release date: 2020-04-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Isoform-selective regulation of mammalian cryptochromes. Nat.Chem.Biol., 16, 2020

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