5EWQ
| The crystal structure of an amidase family protein from Bacillus anthracis str. Ames | Descriptor: | ACETATE ION, Amidase | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-11-20 | Release date: | 2015-12-09 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | The crystal structure of an amidase family protein from Bacillus anthracis str. Ames To Be Published
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6TE4
| Structural insights into Pseudomonas aeruginosa Type six secretion system exported effector 8: Tse8 in complex with a peptide | Descriptor: | Pro-Pro-Leu-Ala-Ser-Lys, Tse8 | Authors: | Sainz-Polo, M.A, Capuni, R, Lucas, M, Altuna, J, Fucini, P, Montanchez, I, Albesa-Jove, D. | Deposit date: | 2019-11-11 | Release date: | 2020-11-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural insights into Pseudomonas aeruginosaType six secretion system exported effector 8. J.Struct.Biol., 212, 2020
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6YHV
| Structural insights into Pseudomonas aeruginosa Type six secretion system exported effector 8: unliganded Tse8 | Descriptor: | COPPER (II) ION, Tse8 | Authors: | Sainz-Polo, M.A, Capuni, R, Pretre, G, Gonzalez-Magana, A, Lucas, M, Altuna, J, Montanchez, I, Fucini, P, Albesa-Jove, D. | Deposit date: | 2020-03-31 | Release date: | 2020-11-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | Structural insights into Pseudomonas aeruginosaType six secretion system exported effector 8. J.Struct.Biol., 212, 2020
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6KVR
| Fatty acid amide hydrolase | Descriptor: | Fatty acid amide hydrolase | Authors: | Min, C.A, Yun, J.S, Chang, J.H. | Deposit date: | 2019-09-05 | Release date: | 2021-09-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Comparison of Candida Albicans Fatty Acid Amide Hydrolase Structure with Homologous Amidase Signature Family Enzymes Crystals, 9, 2019
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2VYA
| Crystal Structure of fatty acid amide hydrolase conjugated with the drug-like inhibitor PF-750 | Descriptor: | 4-(quinolin-3-ylmethyl)piperidine-1-carboxylic acid, CHLORIDE ION, FATTY-ACID AMIDE HYDROLASE 1, ... | Authors: | Mileni, M, Johnson, D.S, Wang, Z, Everdeen, D.S, Liimatta, M, Pabst, B, Bhattacharya, K, Nugent, R.A, Kamtekar, S, Cravatt, B.F, Ahn, K, Stevens, R.C. | Deposit date: | 2008-07-22 | Release date: | 2008-09-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-Guided Inhibitor Design for Human Faah by Interspecies Active Site Conversion. Proc.Natl.Acad.Sci.USA, 105, 2008
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6MRG
| FAAH bound to non covalent inhibitor | Descriptor: | (1R)-2-{[6-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimidin-4-yl]amino}-1-phenylethan-1-ol, Fatty-acid amide hydrolase 1 | Authors: | Saha, A, Shih, A, Mirzadegan, T, Seierstad, M. | Deposit date: | 2018-10-12 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Predicting the Binding of Fatty Acid Amide Hydrolase Inhibitors by Free Energy Perturbation. J Chem Theory Comput, 14, 2018
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4CP8
| Structure of the amidase domain of allophanate hydrolase from Pseudomonas sp strain ADP | Descriptor: | ALLOPHANATE HYDROLASE, MALONATE ION | Authors: | Balotra, S, Newman, J, French, N, French, L, Peat, T.S, Scott, C. | Deposit date: | 2014-02-03 | Release date: | 2014-11-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-Ray Structure of the Amidase Domain of Atzf, the Allophanate Hydrolase from the Cyanuric Acid-Mineralizing Multienzyme Complex. Appl.Environ.Microbiol., 81, 2015
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2WAP
| 3D-crystal structure of humanized-rat fatty acid amide hydrolase (FAAH) conjugated with the drug-like urea inhibitor PF-3845 | Descriptor: | 4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acid, CHLORIDE ION, FATTY-ACID AMIDE HYDROLASE 1, ... | Authors: | Mileni, M, Kamtekar, S, Stevens, R.C. | Deposit date: | 2009-02-11 | Release date: | 2009-05-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery and Characterization of a Highly Selective Faah Inhibitor that Reduces Inflammatory Pain. Chem.Biol., 16, 2009
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4DO3
| Structure of FAAH with a non-steroidal anti-inflammatory drug | Descriptor: | (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CHLORIDE ION, CYCLOHEXANE AMINOCARBOXYLIC ACID, ... | Authors: | Garau, G. | Deposit date: | 2012-02-09 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A Binding Site for Nonsteroidal Anti-inflammatory Drugs in Fatty Acid Amide Hydrolase. J.Am.Chem.Soc., 135, 2013
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4YJI
| The Crystal Structure of a Bacterial Aryl Acylamidase Belonging to the Amidase signature (AS) enzymes family | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Aryl acylamidase, N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL) | Authors: | Choi, I.-G, Lee, S, Park, E.-H, Ko, H.-J, Bang, W.-G. | Deposit date: | 2015-03-03 | Release date: | 2015-11-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal structure analysis of a bacterial aryl acylamidase belonging to the amidase signature enzyme family Biochem.Biophys.Res.Commun., 467, 2015
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4YJ6
| The Crystal Structure of a Bacterial Aryl Acylamidase Belonging to the Amidase signature (AS) enzymes family | Descriptor: | Aryl acylamidase, PHOSPHATE ION | Authors: | Lee, S, Park, E.-H, Ko, H.-J, Bang, W.-G, Choi, I.-G. | Deposit date: | 2015-03-03 | Release date: | 2015-11-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure analysis of a bacterial aryl acylamidase belonging to the amidase signature enzyme family Biochem.Biophys.Res.Commun., 467, 2015
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5AC3
| Crystal structure of PAM12A | Descriptor: | ACETIC ACID, CADMIUM ION, PEPTIDE AMIDASE | Authors: | Wu, B, Wijma, H.J, Song, L, Rozeboom, H.J, Poloni, C, Tian, Y, Arif, M.I, Nuijens, T, Quadflieg, P.J.L.M, Szymanski, W, Feringa, B.L, Janssen, D.B. | Deposit date: | 2015-08-11 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Versatile Peptide C-Terminal Functionalization Via a Computationally Peptide Amidase Acs Catalysis, 2016
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4J5P
| Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase | Descriptor: | (1S)-1-{5-[5-(bromomethyl)pyridin-2-yl]-1,3-oxazol-2-yl}-7-phenylheptan-1-ol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Otrubova, K, Brown, M, McCormick, M.S, Han, G.W, O'Neal, S.T, Cravatt, B.F, Stevens, R.C, Lichtman, A.H, Boger, D.L. | Deposit date: | 2013-02-08 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Rational design of Fatty Acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. J.Am.Chem.Soc., 135, 2013
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4HBP
| Crystal Structure of FAAH in complex with inhibitor | Descriptor: | 4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyridin-3-yl)piperazine-1-carboxamide, Fatty-acid amide hydrolase 1 | Authors: | Behnke, C, Skene, R.J. | Deposit date: | 2012-09-28 | Release date: | 2013-02-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors. Bioorg.Med.Chem., 21, 2013
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2DC0
| Crystal structure of amidase | Descriptor: | probable amidase | Authors: | Ohshima, T, Sakuraba, H, Ebihara, A, Kanagawa, M, Nakagawa, N, Kuroishi, C, Satoh, S, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-17 | Release date: | 2007-01-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of amidase To be Published
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8ES6
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8EWW
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8EY1
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8EY9
| Structure of Arabidopsis fatty acid amide hydrolase mutant S305A in complex with 9-hydroxy-10,12-octadecadienoyl-ethanolamide | Descriptor: | (9R,10E,12Z)-9-hydroxy-N-(2-hydroxyethyl)octadeca-10,12-dienamide, Fatty acid amide hydrolase | Authors: | Aziz, M, Wang, X, Gaguancela, O.A, Chapman, K.D. | Deposit date: | 2022-10-26 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Structural interactions explain the versatility of FAAH in the hydrolysis of plant and microbial acyl amide signals To be published
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6DII
| Structure of Arabidopsis Fatty Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate | Descriptor: | Fatty acid amide hydrolase, methyl-9Z,12Z,15Z-octadecatrienylphosphonofluoridate | Authors: | Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D. | Deposit date: | 2018-05-23 | Release date: | 2019-03-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides. J.Biol.Chem., 294, 2019
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2GI3
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6DHV
| Structure of Arabidopsis Fatty Acid Amide Hydrolase | Descriptor: | Fatty acid amide hydrolase | Authors: | Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D. | Deposit date: | 2018-05-21 | Release date: | 2019-03-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides. J.Biol.Chem., 294, 2019
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3LJ6
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3K84
| Crystal Structure Analysis of a Oleyl/Oxadiazole/pyridine Inhibitor Bound to a Humanized Variant of Fatty Acid Amide Hydrolase | Descriptor: | (9Z)-1-(5-pyridin-2-yl-1,3,4-oxadiazol-2-yl)octadec-9-en-1-one, CHLORIDE ION, Fatty-acid amide hydrolase 1 | Authors: | Mileni, M, Stevens, R.C, Boger, D.L. | Deposit date: | 2009-10-13 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | X-ray crystallographic analysis of alpha-ketoheterocycle inhibitors bound to a humanized variant of fatty acid amide hydrolase. J.Med.Chem., 53, 2010
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3K83
| Crystal Structure Analysis of a Biphenyl/Oxazole/Carboxypyridine alpha-ketoheterocycle Inhibitor Bound to a Humanized Variant of Fatty Acid Amide Hydrolase | Descriptor: | 1-DODECANOL, 6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid, CHLORIDE ION, ... | Authors: | Mileni, M, Stevens, R.C, Boger, D.L. | Deposit date: | 2009-10-13 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | X-ray crystallographic analysis of alpha-ketoheterocycle inhibitors bound to a humanized variant of fatty acid amide hydrolase. J.Med.Chem., 53, 2010
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