6BXG
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![BU of 6bxg by Molmil](/molmil-images/mine/6bxg) | 1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. | Descriptor: | CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ... | Authors: | Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-12-18 | Release date: | 2018-01-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | 1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. To Be Published
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4UU6
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![BU of 4uu6 by Molmil](/molmil-images/mine/4uu6) | CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. | Deposit date: | 2014-07-24 | Release date: | 2015-01-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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3ZRT
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![BU of 3zrt by Molmil](/molmil-images/mine/3zrt) | Crystal structure of human PSD-95 PDZ1-2 | Descriptor: | DISKS LARGE HOMOLOG 4 | Authors: | Sorensen, P.L, Kastrup, J.S, Gajhede, M. | Deposit date: | 2011-06-19 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.398 Å) | Cite: | A High-Affinity, Dimeric Inhibitor of Psd-95 Bivalently Interacts with Pdz1-2 and Protects Against Ischemic Brain Damage. Proc.Natl.Acad.Sci.USA, 109, 2012
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1D5G
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![BU of 1d5g by Molmil](/molmil-images/mine/1d5g) | |
8OEP
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![BU of 8oep by Molmil](/molmil-images/mine/8oep) | Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide | Descriptor: | Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 | Authors: | Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. | Deposit date: | 2023-03-11 | Release date: | 2023-05-10 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
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4N6X
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![BU of 4n6x by Molmil](/molmil-images/mine/4n6x) | Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1 | Descriptor: | CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion protein | Authors: | Lu, G, Wu, Y, Jiang, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. | Deposit date: | 2013-10-14 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.051 Å) | Cite: | New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping. Plos One, 8, 2013
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5TYT
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![BU of 5tyt by Molmil](/molmil-images/mine/5tyt) | Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide | Descriptor: | Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera | Authors: | Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z. | Deposit date: | 2016-11-21 | Release date: | 2017-02-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF. Biochem. Biophys. Res. Commun., 485, 2017
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5K4F
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![BU of 5k4f by Molmil](/molmil-images/mine/5k4f) | CAL PDZ mutant C319A with a peptide | Descriptor: | Golgi-associated PDZ and coiled-coil motif-containing protein, HPV18E6 peptide | Authors: | Zhao, Y, Madden, D.R. | Deposit date: | 2016-05-20 | Release date: | 2017-08-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | CAL PDZ domain mutant with a peptide To Be Published
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8WWR
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![BU of 8wwr by Molmil](/molmil-images/mine/8wwr) | |
8YR7
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![BU of 8yr7 by Molmil](/molmil-images/mine/8yr7) | |
5JXB
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![BU of 5jxb by Molmil](/molmil-images/mine/5jxb) | PSD-95 extended PDZ3 in complex with SynGAP PBM | Descriptor: | Disks large homolog 4,SynGAP | Authors: | Shang, Y, Zhang, M. | Deposit date: | 2016-05-13 | Release date: | 2016-09-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity. Cell, 166, 2016
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6SPZ
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![BU of 6spz by Molmil](/molmil-images/mine/6spz) | |
6SPV
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![BU of 6spv by Molmil](/molmil-images/mine/6spv) | Crystal structure of PDZ1-2 from PSD-95 | Descriptor: | Disks large homolog 4, GLUTATHIONE | Authors: | Rodzli, N, Levy, C.W, Prince, S.M. | Deposit date: | 2019-09-02 | Release date: | 2019-10-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | The Dual PDZ Domain from Postsynaptic Density Protein 95 Forms a Scaffold with Peptide Ligand. Biophys.J., 119, 2020
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7CQF
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8GI4
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![BU of 8gi4 by Molmil](/molmil-images/mine/8gi4) | |
8HCK
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8HU2
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![BU of 8hu2 by Molmil](/molmil-images/mine/8hu2) | Rattus Syntenin-1 PDZ domain with inhibitor | Descriptor: | (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1 | Authors: | Heo, Y, Lee, J, Yun, J.H, Lee, W. | Deposit date: | 2022-12-22 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution. To Be Published
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1BFE
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![BU of 1bfe by Molmil](/molmil-images/mine/1bfe) | THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 | Descriptor: | PSD-95 | Authors: | Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. | Deposit date: | 1998-05-20 | Release date: | 1998-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996
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1B8Q
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![BU of 1b8q by Molmil](/molmil-images/mine/1b8q) | SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE | Descriptor: | PROTEIN (HEPTAPEPTIDE), PROTEIN (NEURONAL NITRIC OXIDE SYNTHASE) | Authors: | Tochio, H, Zhang, Q, Mandal, P, Li, M, Zhang, M. | Deposit date: | 1999-02-01 | Release date: | 1999-04-29 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide. Nat.Struct.Biol., 6, 1999
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7E0B
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1BE9
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![BU of 1be9 by Molmil](/molmil-images/mine/1be9) | THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT. | Descriptor: | CRIPT, PSD-95 | Authors: | Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. | Deposit date: | 1998-05-20 | Release date: | 1998-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996
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7D6F
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![BU of 7d6f by Molmil](/molmil-images/mine/7d6f) | The crystal structure of ARMS-PBM/MAGI2-PDZ4 | Descriptor: | GLYCEROL, Kinase D-interacting substrate of 220 kDa, Membrane-associated guanylate kinase, ... | Authors: | Ye, J, Zhang, Y, Zhong, Z, Wang, C. | Deposit date: | 2020-09-30 | Release date: | 2020-11-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode. Neurochem.Int., 149, 2021
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2W4F
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![BU of 2w4f by Molmil](/molmil-images/mine/2w4f) | CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1 | Descriptor: | 1,2-ETHANEDIOL, PROTEIN LAP4 | Authors: | Hozjan, V, Pilka, E.S, Roos, A.K, W Yue, W, Phillips, C, Bray, J, Cooper, C, Salah, E, Elkins, J.M, Muniz, J.R.C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Bountra, C, Doyle, D.A, Oppermann, U. | Deposit date: | 2008-11-25 | Release date: | 2008-12-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal Structure of the First Pdz Domain of Human Scrib1 To be Published
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2VRF
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![BU of 2vrf by Molmil](/molmil-images/mine/2vrf) | CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN | Descriptor: | 1,2-ETHANEDIOL, BETA-2-SYNTROPHIN | Authors: | Sun, Z, Roos, A.K, Pike, A.C.W, Pilka, E.S, Cooper, C, Elkins, J.M, Murray, J, Arrowsmith, C.H, Doyle, D, Edwards, A, von Delft, F, Bountra, C, Oppermann, U. | Deposit date: | 2008-03-31 | Release date: | 2008-04-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Human Beta-2-Syntrophin Pdz Domain To be Published
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2VPH
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![BU of 2vph by Molmil](/molmil-images/mine/2vph) | Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain | Descriptor: | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 4 | Authors: | Roos, A.K, Wang, J, Burgess-Brown, N, Elkins, J.M, Kavanagh, K, Pike, A.C.W, Filippakopoulos, P, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Bountra, C, Knapp, S. | Deposit date: | 2008-02-29 | Release date: | 2008-03-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Human Protein Tyrosine Phosphatase, Non-Receptor Type 4, Pdz Domain To be Published
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