3CBX
The Dvl2 PDZ Domain in Complex with the C1 Inhibitory Peptide
Summary for 3CBX
| Entry DOI | 10.2210/pdb3cbx/pdb |
| Related | 3CBY 3CBZ 3CC0 |
| Descriptor | Dishevelled-2, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | pdz domain, phage derived high affinity ligand, developmental protein, phosphoprotein, wnt signaling pathway, signaling protein, protein binding |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : O14641 |
| Total number of polymer chains | 2 |
| Total formula weight | 23121.84 |
| Authors | Appleton, B.A.,Wiesmann, C. (deposition date: 2008-02-23, release date: 2009-03-03, Last modification date: 2023-08-30) |
| Primary citation | Zhang, Y.,Appleton, B.A.,Wiesmann, C.,Lau, T.,Costa, M.,Hannoush, R.N.,Sidhu, S.S. Inhibition of Wnt signaling by Dishevelled PDZ peptides Nat.Chem.Biol., 5:217-219, 2009 Cited by PubMed: 19252499DOI: 10.1038/nchembio.152 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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