3CBX

The Dvl2 PDZ Domain in Complex with the C1 Inhibitory Peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Dishevelled-2	polymer	105	11425.0	2	UniProt (O14641) Pfam (PF00595) In PDB	Homo sapiens (Human)	DSH homolog 2, Segment polarity protein dishevelled homolog DVL-2
2	A	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4		water	water		18.0	121	Chemie (HOH)

Sequence modifications

A, B: 264 - 354 (UniProt: O14641)

PDB	External Database	Details
Gly 260	-	expression tag
Ser 261	-	expression tag
His 262	-	expression tag
Met 263	-	expression tag
Ser 354	Cys 354	engineered mutation
Gly 355	-	linker
Gly 356	-	linker
Gly 357	-	linker
Trp 358	-	SEE REMARK 999
Lys 359	-	SEE REMARK 999
Trp 360	-	SEE REMARK 999
Tyr 361	-	SEE REMARK 999
Gly 362	-	SEE REMARK 999
Trp 363	-	SEE REMARK 999
Phe 364	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	22850.0
Non-Polymers*	Number of molecules	3
	Total formula weight	271.8
All*	Total formula weight	23121.8

*Water molecules are not included.