3CBY

The Dvl2 PDZ Domain in Complex with the N1 Inhibitory Peptide

Summary for 3CBY

Entry DOI	10.2210/pdb3cby/pdb
Related	3CBX 3CBZ 3CC0
Descriptor	Dishevelled-2, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	pdz domain, phage derived high affinity ligand, cytoplasm, developmental protein, phosphoprotein, wnt signaling pathway, protein binding
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : O14641
Total number of polymer chains	2
Total formula weight	23366.54
Authors	Appleton, B.A.,Wiesmann, C. (deposition date: 2008-02-23, release date: 2009-03-03, Last modification date: 2023-08-30)
Primary citation	Zhang, Y.,Appleton, B.A.,Wiesmann, C.,Lau, T.,Costa, M.,Hannoush, R.N.,Sidhu, S.S. Inhibition of Wnt signaling by Dishevelled PDZ peptides Nat.Chem.Biol., 5:217-219, 2009 Cited by PubMed: 19252499 DOI: 10.1038/nchembio.152 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation