3CBY

The Dvl2 PDZ Domain in Complex with the N1 Inhibitory Peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Dishevelled-2	polymer	108	11621.2	2	UniProt (O14641) Pfam (PF00595) In PDB	Homo sapiens (Human)	Segment polarity protein dishevelled homolog DVL-2, DSH homolog 2
2	A, B	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
3		water	water		18.0	198	Chemie (HOH)

Sequence modifications

A, B: 264 - 354 (UniProt: O14641)

PDB	External Database	Details
Gly 260	-	expression tag
Ser 261	-	expression tag
His 262	-	expression tag
Met 263	-	expression tag
Ser 354	Cys 354	engineered mutation
Gly 355	-	linker
Gly 356	-	linker
Gly 357	-	linker
Trp 358	-	SEE REMARK 999
Lys 359	-	SEE REMARK 999
Asp 360	-	SEE REMARK 999
Tyr 361	-	SEE REMARK 999
Gly 362	-	SEE REMARK 999
Trp 363	-	SEE REMARK 999
Ile 364	-	SEE REMARK 999
Asp 365	-	SEE REMARK 999
Gly 366	-	SEE REMARK 999
Lys 367	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23242.4
Non-Polymers*	Number of molecules	2
	Total formula weight	124.1
All*	Total formula weight	23366.5

*Water molecules are not included.