7ZGO
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![BU of 7zgo by Molmil](/molmil-images/mine/7zgo) | Cryo-EM structure of human NKCC1 (TM domain) | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Nissen, P, Fenton, R, Neumann, C, Lindtoft Rosenbaek, L, Kock Flygaard, R, Habeck, M, Lykkegaard Karlsen, J, Wang, Y, Lindorff-Larsen, K, Gad, H, Hartmann, R, Lyons, J. | Deposit date: | 2022-04-04 | Release date: | 2022-10-05 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity. Embo J., 41, 2022
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7S1X
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![BU of 7s1x by Molmil](/molmil-images/mine/7s1x) | |
7SMP
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![BU of 7smp by Molmil](/molmil-images/mine/7smp) | CryoEM structure of NKCC1 Bu-I | Descriptor: | 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, POTASSIUM ION, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-10-26 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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7S1Z
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![BU of 7s1z by Molmil](/molmil-images/mine/7s1z) | Cryo-EM structure of Human NKCC1 K289NA492EL671C | Descriptor: | Solute carrier family 12 member 2 | Authors: | Zhao, Y.X, Cao, E.H. | Deposit date: | 2021-09-02 | Release date: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide Nat Commun, 13, 2022
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7N3N
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![BU of 7n3n by Molmil](/molmil-images/mine/7n3n) | CryoEM structure of human NKCC1 state Fu-I | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-06-01 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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8STE
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![BU of 8ste by Molmil](/molmil-images/mine/8ste) | Cryo-EM structure of NKCC1 Fu_CTD | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2023-05-10 | Release date: | 2023-05-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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6PZT
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![BU of 6pzt by Molmil](/molmil-images/mine/6pzt) | cryo-EM structure of human NKCC1 | Descriptor: | Solute carrier family 12 member 2 | Authors: | Cao, E, Wang, Q, Yang, X. | Deposit date: | 2019-08-01 | Release date: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. Nat Commun, 11, 2020
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7MXO
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![BU of 7mxo by Molmil](/molmil-images/mine/7mxo) | CryoEM structure of human NKCC1 | Descriptor: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-05-19 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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7D10
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![BU of 7d10 by Molmil](/molmil-images/mine/7d10) | Human NKCC1 | Descriptor: | PALMITIC ACID, Solute carrier family 12 member 2 | Authors: | Zhang, S, Yang, M. | Deposit date: | 2020-09-12 | Release date: | 2021-04-14 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2. Commun Biol, 4, 2021
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7S1Y
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![BU of 7s1y by Molmil](/molmil-images/mine/7s1y) | |
7SFL
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![BU of 7sfl by Molmil](/molmil-images/mine/7sfl) | Human NKCC1 state Fu-II | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-10-04 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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