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6RT5
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The YTH domain of YTHDC1 protein in complex with Gm6AC oligonucleotide
分子名称: RNA (5'-R(*(6MZ)P*C)-3'), SULFATE ION, YTH domain-containing protein 1
著者Bedi, R, Sledz, P, Caflisch, A.
登録日2019-05-22
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif.
J Chem Theory Comput, 15, 2019
6LR2
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SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-2 CONTAINING PROTEIN 2
分子名称: YTH domain containing protein 2 (YTHDC2)
著者Muto, Y, Kobayashi, N, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2020-01-15
公開日2021-01-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-CONTAINING PROTEIN 2
TO BE PUBLISHED
4WQN
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BU of 4wqn by Molmil
Crystal structure of N6-methyladenosine RNA reader YTHDF2
分子名称: 1,2-ETHANEDIOL, GLYCEROL, YTH domain-containing family protein 2
著者Zhu, T, Roundtree, I.A, Wang, P, Wang, X, Wang, L, Sun, C, Tian, Y, Li, J, He, C, Xu, Y.
登録日2014-10-22
公開日2014-11-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.121 Å)
主引用文献Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.
Cell Res., 24, 2014
4U8T
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BU of 4u8t by Molmil
Crystal structure of YTH domain of Zygosaccharomyces rouxii MRB1 protein in complex with N6-Methyladenosine RNA
分子名称: RNA (5'-R(*AP*GP*GP*(6MZ)P*CP*AP*U)-3'), ZYRO0G01672p
著者Luo, S, Tong, L.
登録日2014-08-04
公開日2014-09-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain.
Proc.Natl.Acad.Sci.USA, 111, 2014
5ZUU
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BU of 5zuu by Molmil
Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA
分子名称: 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
著者Wu, B, Nie, H, Li, S, Patel, D.J.
登録日2018-05-08
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis.
Mol Plant, 2021
7BIK
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BU of 7bik by Molmil
Crystal structure of YTHDF2 in complex with m6Am
分子名称: (2~{R},3~{S},4~{R},5~{R})-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol, GLYCEROL, SULFATE ION, ...
著者Wang, X, Caflisch, A.
登録日2021-01-12
公開日2021-11-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of YTHDF2 in complex with m6Am
To Be Published
5O8M
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Crystal structure of the MmI1 YTH domain
分子名称: GLYCEROL, YTH domain-containing protein mmi1
著者Brettschneider, J, Verdel, A, Kadlec, J.
登録日2017-06-13
公開日2018-04-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.
EMBO J., 36, 2017
6K6U
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BU of 6k6u by Molmil
Crystal structure of the human YTHDC2 YTH domain
分子名称: 3'-5' RNA helicase YTHDC2
著者Ma, C, Liao, S, Xu, C.
登録日2019-06-04
公開日2019-12-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure of human YTHDC2 YTH domain.
Biochem.Biophys.Res.Commun., 518, 2019
2MTV
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BU of 2mtv by Molmil
Solution Structure of the YTH Domain of YT521-B in complex with N6-Methyladenosine containing RNA
分子名称: RNA_(5'-R(*UP*GP*(6MZ)P*CP*AP*C)-3'), YTH domain-containing protein 1
著者Theler, D, Dominguez, C, Blatter, M, Boudet, J, Allain, F.H.-T.
登録日2014-09-01
公開日2014-11-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA.
Nucleic Acids Res., 42, 2014
2YUD
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BU of 2yud by Molmil
Solution structure of the YTH domain in YTH domain-containing protein 1 (Putative splicing factor YT521)
分子名称: YTH domain-containing protein 1
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-06
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the YTH domain in YTH domain-containing protein 1 (Putative splicing factor YT521)
To be Published
2YU6
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BU of 2yu6 by Molmil
Solution structure of the YTH domain in YTH domain-containing protein 2
分子名称: YTH domain-containing protein 2
著者Endo, R, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the YTH domain in YTH domain-containing protein 2
To be Published
7A1V
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BU of 7a1v by Molmil
Crystal structure of YTHDF2 in complex with m1A
分子名称: 6-AMINO-1-METHYLPURINE, GLYCEROL, SULFATE ION, ...
著者Wang, X, Caflisch, A.
登録日2020-08-14
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of YTHDF2 in complex with m1A
To Be Published
6ZOT
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BU of 6zot by Molmil
Crystal structure of YTHDF3 YTH domain in complex with m6A RNA
分子名称: RNA, YTH domain-containing family protein 3
著者Bedi, R.K, Caflisch, A.
登録日2020-07-07
公開日2020-10-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Dynamic Insights into Redundant Function of YTHDF Proteins.
J.Chem.Inf.Model., 60, 2020
5H8A
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BU of 5h8a by Molmil
Mmi1 YTH domain
分子名称: YTH domain-containing protein mmi1
著者Chatterjee, D, Goldgur, Y, Shuman, S.
登録日2015-12-23
公開日2016-01-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast.
Rna, 22, 2016
5HFZ
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BU of 5hfz by Molmil
Mmi1 YTH domain
分子名称: YTH domain-containing protein mmi1
著者Chatterjee, D, Goldgur, Y, Shuman, S.
登録日2016-01-07
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast.
Rna, 22, 2016
7L4X
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BU of 7l4x by Molmil
YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by two six-bp DNA duplexes in P3221 Crystal
分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA w/N6A
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
7L4Y
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YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by Two Six-bp DNA Duplexes in P212121 Crystal
分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA 13mer
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
8BS6
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BU of 8bs6 by Molmil
Crystal structure of YTHDF3 disulfide mutant (closed conformation)
分子名称: YTH domain-containing family protein 3
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2022-11-24
公開日2023-12-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structure of YTHDF3 disulfide mutant (closed conformation)
To Be Published
8BS5
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BU of 8bs5 by Molmil
Crystal structure of YTHDF3 YTH domain open conformation
分子名称: DI(HYDROXYETHYL)ETHER, L(+)-TARTARIC ACID, YTH domain-containing family protein 3
著者Bedi, R.K, Caflisch, A.
登録日2022-11-24
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal structure of YTHDF3 YTH domain open conformation
To Be Published
8BS4
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BU of 8bs4 by Molmil
Crystal structure of YTHDF1 YTH domain dimer
分子名称: ACETATE ION, GLYCEROL, YTH domain-containing family protein 1
著者Bedi, R.K, Caflisch, A.
登録日2022-11-24
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of YTHDF1 YTH domain dimer
To Be Published
7NG2
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BU of 7ng2 by Molmil
Crystal structure of Toxoplasma CPSF4-YTH domain in apo form
分子名称: ISOPROPYL ALCOHOL, Zinc finger (CCCH type) motif-containing protein
著者Swale, C, Bowler, M.W.
登録日2021-02-08
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .
Elife, 10, 2021
7NJC
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BU of 7njc by Molmil
Crystal structure of the Toxoplasma CPSF4 YTH-domain in complex with a 7 mer m6A-modified RNA
分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, N-methyladenosine, RNA (5'-R(*(6MZ)P*CP*A)-3'), ...
著者Swale, C, Bowler, M.W.
登録日2021-02-16
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .
Elife, 10, 2021
7NH2
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Crystal structure of Toxoplasma CPSF4-YTH domain bound to m6A
分子名称: TETRAETHYLENE GLYCOL, Zinc finger (CCCH type) motif-containing protein, ~{N},9-dimethylpurin-6-amine
著者Swale, C, Bowler, M.W.
登録日2021-02-09
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .
Elife, 10, 2021
6FPP
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Structure of S. pombe Mmi1
分子名称: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1
著者Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
登録日2018-02-11
公開日2018-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPQ
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Structure of S. pombe Mmi1 in complex with 7-mer RNA
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1
著者Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
登録日2018-02-11
公開日2018-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018

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