7NH2

Crystal structure of Toxoplasma CPSF4-YTH domain bound to m6A

Summary for 7NH2

• Entry DOI: 10.2210/pdb7nh2/pdb
• Related: 7NG2
• Descriptor: Zinc finger (CCCH type) motif-containing protein, TETRAETHYLENE GLYCOL, ~{N},9-dimethylpurin-6-amine, ... (4 entities in total)
• Functional Keywords: yth, cleavage and polyadenylation, rna, m6a, rna binding protein
• Biological source: Toxoplasma gondii (strain ATCC 50611 / Me49)
• Total number of polymer chains: 1
• Total formula weight: 18805.40

Authors

Swale, C.,Bowler, M.W. (deposition date: 2021-02-09, release date: 2021-07-21, Last modification date: 2024-01-31)

• Primary citation: Farhat, D.C.,Bowler, M.W.,Communie, G.,Pontier, D.,Belmudes, L.,Mas, C.,Corrao, C.,Coute, Y.,Bougdour, A.,Lagrange, T.,Hakimi, M.A.,Swale, C.; A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .; Elife, 10:-, 2021; PubMed: 34263725; DOI: 10.7554/eLife.68312

Experimental method

X-RAY DIFFRACTION (1.35 Å)