7NJC

Crystal structure of the Toxoplasma CPSF4 YTH-domain in complex with a 7 mer m6A-modified RNA

Summary for 7NJC

• Entry DOI: 10.2210/pdb7njc/pdb
• Related: 7NG2 7NH2
• Descriptor: Zinc finger (CCCH type) motif-containing protein, RNA (5'-R(*(6MZ)P*CP*A)-3'), 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ... (5 entities in total)
• Functional Keywords: yth, cleavage and polyadenylation, rna, m6a, rna recognition protein, rna binding protein
• Biological source: Toxoplasma gondii (strain ATCC 50611 / Me49); More
• Total number of polymer chains: 2
• Total formula weight: 21112.87

Authors

Swale, C.,Bowler, M.W. (deposition date: 2021-02-16, release date: 2021-07-21, Last modification date: 2024-01-31)

• Primary citation: Farhat, D.C.,Bowler, M.W.,Communie, G.,Pontier, D.,Belmudes, L.,Mas, C.,Corrao, C.,Coute, Y.,Bougdour, A.,Lagrange, T.,Hakimi, M.A.,Swale, C.; A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma .; Elife, 10:-, 2021; PubMed: 34263725; DOI: 10.7554/eLife.68312

Experimental method

X-RAY DIFFRACTION (1.38 Å)