7NJC
Crystal structure of the Toxoplasma CPSF4 YTH-domain in complex with a 7 mer m6A-modified RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Zinc finger (CCCH type) motif-containing protein | polymer | 166 | 18448.0 | 1 | UniProt (S8F6K2) Pfam (PF04146) | Toxoplasma gondii (strain ATCC 50611 / Me49) | CPSF4 |
| 2 | B (B) | RNA (5'-R(*(6MZ)P*CP*A)-3') | polymer | 7 | 2219.4 | 1 | synthetic construct | ||
| 3 | C (A) | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL | non-polymer | 164.2 | 1 | Chemie (TOE) PubChem (8178) | |||
| 4 | D (B) | N-methyladenosine | non-polymer | 281.3 | 1 | Chemie (6MD) PubChem (34365247) PubChem (40467934) PubChem (44398080) PubChem (46874073) PubChem (51397493) PubChem (51397494) PubChem (1869) PubChem (57205233) PubChem (138457037) PubChem (101382) PubChem (102175) PubChem (118492824) PubChem (124338918) PubChem (5284425) PubChem (129359906) PubChem (11957602) PubChem (152175003) PubChem (13830713) PubChem (162472624) PubChem (171699464) | |||
| 5 | E (A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 434 - 598 (UniProt: S8F6K2)
| PDB | External Database | Details |
|---|---|---|
| Gly 433 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20667.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 445.5 | |
| All* | Total formula weight | 21112.9 |
