7NJC
Crystal structure of the Toxoplasma CPSF4 YTH-domain in complex with a 7 mer m6A-modified RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Zinc finger (CCCH type) motif-containing protein | polymer | 166 | 18448.0 | 1 | UniProt (S8F6K2) Pfam (PF04146) In PDB | Toxoplasma gondii (strain ATCC 50611 / Me49) | CPSF4 |
| 2 | B | RNA (5'-R(*(6MZ)P*CP*A)-3') | polymer | 7 | 2219.4 | 1 | synthetic construct | ||
| 3 | A | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL | non-polymer | 164.2 | 1 | Chemie (TOE) | |||
| 4 | B | N-methyladenosine | non-polymer | 281.3 | 1 | Chemie (6MD) | |||
| 5 | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 434 - 598 (UniProt: S8F6K2)
| PDB | External Database | Details |
|---|---|---|
| Gly 433 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20667.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 445.5 | |
| All* | Total formula weight | 21112.9 |
