PDB: 153 件ウェブページステータス検索Chemie searchBIRD

---

6FVB	Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae 分子名称: Importin beta-like protein KAP120 著者 Vera Rodriguez, A, Huyton, T, Gorlich, D. 登録日 2018-03-01 公開日 2019-09-11 実験手法 X-RAY DIFFRACTION (3.297 Å) 主引用文献 Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae To Be Published
6AHO	Crystal structure of Kap114p 分子名称: Importin subunit beta-5 著者 Liao, C.C, Shankar, S, Ahmed, G.R, Hsia, K.C. 登録日 2018-08-20 公開日 2019-10-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress. Embo Rep., 21, 2020
4XRI	Crystal Structure of Importin Beta in an Ammonium Sulfate Condition 分子名称: GLYCEROL, Putative uncharacterized protein, SULFATE ION 著者 Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A. 登録日 2015-01-21 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Impact of the crystallization condition on importin-beta conformation. Acta Crystallogr D Struct Biol, 72, 2016
4XRK	Crystal Structure of Importin Beta in a Polyethylene Glycol Condition 分子名称: Importin Beta 著者 Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A. 登録日 2015-01-21 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Impact of the crystallization condition on importin-beta conformation. Acta Crystallogr D Struct Biol, 72, 2016
1GCJ	N-TERMINAL FRAGMENT OF IMPORTIN-BETA 分子名称: IMPORTIN BETA 著者 Lee, S.J, Imamoto, N, Sakai, H, Nakagawa, A, Kose, S, Koike, M, Yamamoto, M, Kumasaka, T, Yoneda, Y, Tsukihara, T. 登録日 2000-07-31 公開日 2000-10-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport. J.Mol.Biol., 302, 2000
4BSN	Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.1A 分子名称: EXPORTIN-1 著者 Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C. 登録日 2013-06-11 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix. Structure, 21, 2013
3GB8	Crystal structure of CRM1/Snurportin-1 complex 分子名称: Exportin-1, Snurportin-1 著者 Dong, X, Biswas, A, Suel, K.E, Jackson, L.K, Martinez, R, Gu, H, Chook, Y.M. 登録日 2009-02-19 公開日 2009-03-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for leucine-rich nuclear export signal recognition by CRM1. Nature, 458, 2009
3VYC	Crystal structure of unliganded Saccharomyces cerevisiae CRM1 (Xpo1p) 分子名称: Exportin-1 著者 Saito, N, Matsuura, Y. 登録日 2012-09-22 公開日 2012-11-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A 2.1- angstrom -resolution crystal structure of unliganded CRM1 reveals the mechanism of autoinhibition J.Mol.Biol., 425, 2013
3ZKV	Importin13 cytosolic state 分子名称: CADMUS 著者 Gruenwald, M, Lazzaretti, D, Bono, F. 登録日 2013-01-24 公開日 2013-04-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Basis for the Nuclear Export Activity of Importin13. Embo J., 32, 2013
4BSM	Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.5A 分子名称: EXPORTIN-1 著者 Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C. 登録日 2013-06-10 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix. Structure, 21, 2013
5YU7	CRYSTAL STRUCTURE OF EXPORTIN-5 分子名称: Exportin-5 著者 Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E. 登録日 2017-11-20 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 Structural Basis for Selective Binding of Export Cargoes by Exportin-5 Structure, 26, 2018
3LWW	Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1 IBB-domain trapped in the same crystallographic asymmetric unit 分子名称: Importin subunit beta-1, Snurportin-1 著者 Bhardwaj, A, Cingolani, G. 登録日 2010-02-24 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta. Biochemistry, 49, 2010
5OWU	Kap95:Nup1 complex 分子名称: Importin subunit beta-1, Nucleoporin NUP1 著者 Stewart, M. 登録日 2017-09-04 公開日 2017-10-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p. J. Mol. Biol., 349, 2005
8ITV	KL2.1 in complex with CRM1-Ran-RanBP1 分子名称: (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{S})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoic acid, ACETATE ION, CHLORIDE ION, ... 著者 Sun, Q, Jian, L. 登録日 2023-03-23 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 KL2.1 in complex with CRM1-Ran-RanBP1 To Be Published
5W0V	Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H4 1-34 分子名称: Histone H4 1-34, Kap123 著者 An, S, Yoon, J, Song, J.-J, Cho, U.-S. 登録日 2017-05-31 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.821 Å) 主引用文献 Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123. Elife, 6, 2017
4GMX	Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-08-16 公開日 2012-10-17 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood, 120, 2012
8SGH	Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS 分子名称: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1 著者 Gonzalez, A, Fung, H.Y.J, Chook, Y.M. 登録日 2023-04-12 公開日 2023-06-14 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders. Structure, 31, 2023
7YPZ	Zafirlukast in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... 著者 Sun, Q, Lei, Y. 登録日 2022-08-05 公開日 2023-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach. J.Med.Chem., 66, 2023
7L5E	Crystal Structure of KPT-330 bound to CRM1 (537-DLTVK-541 to GLCEQ) 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Baumhardt, J.M, Chook, Y.M. 登録日 2020-12-21 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.944 Å) 主引用文献 Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
2BKU	Kap95p:RanGTP complex 分子名称: GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN BETA-1 SUBUNIT, ... 著者 Lee, S.J, Matsuura, Y, Liu, S.M, Stewart, M. 登録日 2005-02-21 公開日 2005-05-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis for Nuclear Import Complex Dissociation by Rangtp Nature, 435, 2005
7UNK	Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex 分子名称: Histone H3, Histone H4, Histone chaperone, ... 著者 Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y. 登録日 2022-04-11 公開日 2022-09-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex. Proc.Natl.Acad.Sci.USA, 119, 2022
6TVO	Human CRM1-RanGTP in complex with Leptomycin B 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Shaikhqasem, A, Ficner, R. 登録日 2020-01-10 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Characterization of Inhibition Reveals Distinctive Properties for Human andSaccharomyces cerevisiaeCRM1. J.Med.Chem., 63, 2020
7VPW	Crystal structure of Transportin-1 in complex with BAP1 PY-NLS (residues 706-724) 分子名称: BRCA1-associated protein 1 (BAP1), Transportin-1 著者 Yang, T.J, Hsu, S.T.D. 登録日 2021-10-18 公開日 2022-04-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.76 Å) 主引用文献 Tumor suppressor BAP1 nuclear import is governed by transportin-1. J.Cell Biol., 221, 2022
6KFT	MVM NS2 mutant Nm42 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Sun, Q, Li, Y. 登録日 2019-07-08 公開日 2020-07-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
4OO6	Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) 分子名称: RNA-binding protein 39, Transportin-1 著者 Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) 登録日 2014-01-30 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) to be published

 

1234567>