7B51

Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528

Summary for 7B51

Entry DOI	10.2210/pdb7b51/pdb
Descriptor	GTP-binding nuclear protein Ran, Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	exportin, inhibition, nuclear protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	143374.38
Authors	Shaikhqasem, A.,Ficner, R. (deposition date: 2020-12-03, release date: 2021-03-10, Last modification date: 2024-01-31)
Primary citation	Shaikhqasem, A.,Schmitt, K.,Valerius, O.,Ficner, R. Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP. Acta Crystallogr.,Sect.F, 77:70-78, 2021 Cited by PubMed: 33682791 DOI: 10.1107/S2053230X2100203X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.58 Å)

Structure validation