7B51
Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528
Summary for 7B51
Entry DOI | 10.2210/pdb7b51/pdb |
Descriptor | GTP-binding nuclear protein Ran, Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | exportin, inhibition, nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 143374.38 |
Authors | Shaikhqasem, A.,Ficner, R. (deposition date: 2020-12-03, release date: 2021-03-10, Last modification date: 2024-01-31) |
Primary citation | Shaikhqasem, A.,Schmitt, K.,Valerius, O.,Ficner, R. Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP. Acta Crystallogr.,Sect.F, 77:70-78, 2021 Cited by PubMed: 33682791DOI: 10.1107/S2053230X2100203X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
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