6QGS
| Crystal structure of APT1 bound to palmitic acid. | 分子名称: | Acyl-protein thioesterase 1, CHLORIDE ION, PALMITIC ACID | 著者 | Audagnotto, M, Marcaida, M.J, Ho, S, Pojer, F, Van der Goot, G, Dal Peraro, M. | 登録日 | 2019-01-12 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | 主引用文献 | Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Nat.Chem.Biol., 2021
|
|
6QGQ
| Crystal structure of APT1 C2S mutant bound to palmitic acid. | 分子名称: | Acyl-protein thioesterase 1, GLYCEROL, PALMITIC ACID | 著者 | Audagnotto, M, Marcaida, M.J, Ho, S, Pojer, F, Van der Goot, G, Dal Peraro, M. | 登録日 | 2019-01-12 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Nat.Chem.Biol., 2021
|
|
6QGO
| Crystal structure of APT1 S119A mutant bound to palmitic acid. | 分子名称: | Acyl-protein thioesterase 1, PALMITIC ACID | 著者 | Audagnotto, M, Marcaida, M.J, Ho, S, Pojer, F, Van der Goot, G, Dal Peraro, M. | 登録日 | 2019-01-12 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | 主引用文献 | Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Nat.Chem.Biol., 2021
|
|
6QGN
| Crystal structure of APT1 bound to 2-Bromopalmitate | 分子名称: | 2-Bromopalmitic acid, Acyl-protein thioesterase 1 | 著者 | Marcaida, M.J, Audagnotto, M, Ho, S, Pojer, F, Van der Goot, G, Dal Peraro, M. | 登録日 | 2019-01-12 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Nat.Chem.Biol., 2021
|
|
6BJE
| |
6AVY
| |
6AVX
| |
6AVW
| |
6AVV
| |
5SYN
| Cocrystal structure of the human acyl protein thioesterase 2 with an isoform-selective inhibitor, ML349 | 分子名称: | 1,2-ETHANEDIOL, 2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-5lambda~6~-thieno[3,2-c][1]benzothiopyran-5,5(4H)-dione, Acyl-protein thioesterase 2 | 著者 | Stuckey, J.A, Labby, K.J, Meagher, J.L, Won, S.J, Martin, B.R. | 登録日 | 2016-08-11 | 公開日 | 2016-10-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2). ACS Chem. Biol., 11, 2016
|
|
5SYM
| Cocrystal structure of the human acyl protein thioesterase 1 with an isoform-selective inhibitor, ML348 | 分子名称: | 1,2-ETHANEDIOL, Acyl-protein thioesterase 1, CHLORIDE ION, ... | 著者 | Stuckey, J.A, Labby, K.J, Meagher, J.L, Won, S.J, Martin, B.R. | 登録日 | 2016-08-11 | 公開日 | 2016-10-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2). ACS Chem. Biol., 11, 2016
|
|
5KRE
| Covalent inhibitor of LYPLAL1 | 分子名称: | (2~{R})-2-phenylpiperidine-1-carbaldehyde, Lysophospholipase-like protein 1, NITRATE ION | 著者 | Pandit, J. | 登録日 | 2016-07-07 | 公開日 | 2016-07-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. Acs Chem.Biol., 11, 2016
|
|
5F2H
| 2.75 Angstrom resolution crystal structure of uncharacterized protein from Bacillus cereus ATCC 10987 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Uncharacterized protein | 著者 | Halavaty, A.S, Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-12-01 | 公開日 | 2015-12-16 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | 2.75 Angstrom resolution crystal structure of uncharacterized protein from Bacillus cereus ATCC 10987 To Be Published
|
|
5DWD
| Crystal structure of esterase PE8 | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Esterase, GLYCEROL | 著者 | Li, J, Huang, J. | 登録日 | 2015-09-22 | 公開日 | 2016-10-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structure of esterase PE8 To Be Published
|
|
4H0C
| Crystal structure of phospholipase/Carboxylesterase from Dyadobacter fermentans DSM 18053 | 分子名称: | CITRIC ACID, GLYCEROL, Phospholipase/Carboxylesterase, ... | 著者 | Chang, C, Holowicki, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2012-09-07 | 公開日 | 2012-09-26 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Crystal structure of phospholipase/Carboxylesterase from Dyadobacter fermentans DSM 18053 To be Published
|
|
4FTW
| Crystal structure of a carboxyl esterase N110C/L145H at 2.3 angstrom resolution | 分子名称: | 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, CHLORIDE ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ... | 著者 | Wu, L, Ma, J, Zhou, J, Yu, H. | 登録日 | 2012-06-28 | 公開日 | 2012-10-03 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution. Appl.Microbiol.Biotechnol., 97, 2013
|
|
4FHZ
| Crystal structure of a carboxyl esterase at 2.0 angstrom resolution | 分子名称: | DI(HYDROXYETHYL)ETHER, Phospholipase/Carboxylesterase, SODIUM ION | 著者 | Wu, L, Ma, J, Zhou, J, Yu, H. | 登録日 | 2012-06-07 | 公開日 | 2012-10-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution. Appl.Microbiol.Biotechnol., 97, 2013
|
|
4F21
| Crystal structure of carboxylesterase/phospholipase family protein from Francisella tularensis | 分子名称: | Carboxylesterase/phospholipase family protein, N-((1R,2S)-2-allyl-4-oxocyclobutyl)-4-methylbenzenesulfonamide, bound form | 著者 | Filippova, E.V, Minasov, G, Kuhn, M, Wawrzak, Z, Shuvalova, L, Dubrovska, I, Winsor, J.R, Kiryukhina, O, Becker, D.P, Armoush, N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-05-07 | 公開日 | 2012-08-29 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis. J.Biol.Chem., 288, 2013
|
|
3U0V
| Crystal Structure Analysis of human LYPLAL1 | 分子名称: | Lysophospholipase-like protein 1 | 著者 | Burger, M, Zimmermann, T.J, Kondoh, Y, Stege, P, Watanabe, N, Osada, H, Waldmann, H, Vetter, I.R. | 登録日 | 2011-09-29 | 公開日 | 2011-11-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases J.Lipid Res., 53, 2012
|
|
3DOI
| Crystal Structure of a Thermostable Esterase complex with paraoxon | 分子名称: | DIETHYL PHOSPHONATE, esterase | 著者 | Levisson, M, Sun, L, Hendriks, S, Dijkstra, B.W, Van der Oost, J, Kengen, S.W.M. | 登録日 | 2008-07-04 | 公開日 | 2009-02-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain. J.Mol.Biol., 385, 2009
|
|
3DOH
| Crystal Structure of a Thermostable Esterase | 分子名称: | SULFATE ION, esterase | 著者 | Levisson, M, Sun, L, Hendriks, S, Dijkstra, B.W, Van der Oost, J, Kengen, S.W.M. | 登録日 | 2008-07-04 | 公開日 | 2009-02-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain. J.Mol.Biol., 385, 2009
|
|
3CN9
| |
3CN7
| |
2H1I
| Crystal Structure of the Bacillus cereus Carboxylesterase | 分子名称: | CALCIUM ION, CHLORIDE ION, Carboxylesterase, ... | 著者 | Minasov, G, Shuvalova, L, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-05-16 | 公開日 | 2006-05-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of the Bacillus cereus Carboxylesterase To be Published
|
|
1FJ2
| Crystal structure of the human acyl protein thioesterase 1 at 1.5 A resolution | 分子名称: | BROMIDE ION, PROTEIN (ACYL PROTEIN THIOESTERASE 1) | 著者 | Devedjiev, Y, Dauter, Z, Kuznetsov, S, Jones, T, Derewenda, Z. | 登録日 | 2000-08-07 | 公開日 | 2000-11-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A. Structure Fold.Des., 8, 2000
|
|