6QGN

Crystal structure of APT1 bound to 2-Bromopalmitate

Summary for 6QGN

Entry DOI	10.2210/pdb6qgn/pdb
Descriptor	Acyl-protein thioesterase 1, 2-Bromopalmitic acid (3 entities in total)
Functional Keywords	acyl-protein thioesterase 2-bromopalmitate depalmitoylation, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	101252.50
Authors	Marcaida, M.J.,Audagnotto, M.,Ho, S.,Pojer, F.,Van der Goot, G.,Dal Peraro, M. (deposition date: 2019-01-12, release date: 2020-02-05, Last modification date: 2024-01-24)
Primary citation	Abrami, L.,Audagnotto, M.,Ho, S.,Marcaida, M.J.,Mesquita, F.S.,Anwar, M.U.,Sandoz, P.A.,Fonti, G.,Pojer, F.,Dal Peraro, M.,van der Goot, F.G. Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Nat.Chem.Biol., 2021 Cited by PubMed: 33707782 DOI: 10.1038/s41589-021-00753-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.099 Å)

Structure validation