6QGQ
Crystal structure of APT1 C2S mutant bound to palmitic acid.
Summary for 6QGQ
| Entry DOI | 10.2210/pdb6qgq/pdb |
| Related | 6QGN 6QGO |
| Descriptor | Acyl-protein thioesterase 1, GLYCEROL, PALMITIC ACID, ... (5 entities in total) |
| Functional Keywords | acyl-protein thioesterase, palmitic acid, depalmitoylation, hydrolase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 100863.52 |
| Authors | Audagnotto, M.,Marcaida, M.J.,Ho, S.,Pojer, F.,Van der Goot, G.,Dal Peraro, M. (deposition date: 2019-01-12, release date: 2020-02-05, Last modification date: 2024-01-24) |
| Primary citation | Abrami, L.,Audagnotto, M.,Ho, S.,Marcaida, M.J.,Mesquita, F.S.,Anwar, M.U.,Sandoz, P.A.,Fonti, G.,Pojer, F.,Dal Peraro, M.,van der Goot, F.G. Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Nat.Chem.Biol., 2021 Cited by PubMed: 33707782DOI: 10.1038/s41589-021-00753-2 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.601 Å) |
Structure validation
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