PDB: 46 件ウェブページステータス検索Chemie searchBIRD

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8VDP	Cryogenic electron microscopy model of full-length talin without FABD 分子名称: Green fluorescent protein,Talin-1 著者 Izard, T, Rangarajan, E.S. 登録日 2023-12-17 公開日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 High-resolution snapshots of talin auto-inhibitory states To be published
8VDQ	Cryogenic electron microscopy model of full-length talin 分子名称: Green fluorescent protein,Talin-1 著者 Izard, T, Rangarajan, E.S. 登録日 2023-12-17 公開日 2024-10-02 実験手法 ELECTRON MICROSCOPY (5.5 Å) 主引用文献 High-Resolution snapshots of talin auto-inhibitory states To be published
8VDR	Cryogenic electron microscopy model of full-length talin without R12 and FABD 分子名称: Green fluorescent protein,Talin-1 著者 Izard, T, Rangarajan, E.S. 登録日 2023-12-17 公開日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 High-resolution snapshots of talin auto-inhibitory states To be published
8VDO	Cryogenic electron microscopy model of full-length talin lacking F2, R12 and FABD. 分子名称: Green fluorescent protein,Talin-1 著者 Izard, T, Rangarajan, E.S. 登録日 2023-12-16 公開日 2024-10-02 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 High-resolution snapshots of talin auto-inhibitory states To be published
8T0D	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation 分子名称: Integrin beta-2,Talin-1 著者 Wu, J, Gao, T. 登録日 2023-05-31 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
8FTB	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with a K306Q mutation 分子名称: Integrin beta-2,Talin-1 著者 Wu, J, Gao, T. 登録日 2023-01-11 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
8FSE	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain 分子名称: Integrin beta-2,Talin-1 著者 Wu, J, Gao, T. 登録日 2023-01-09 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
6VGU	Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin 分子名称: Integrin beta-3,Talin-1 著者 Zhang, P, Sun, Y, Wu, J. 登録日 2020-01-09 公開日 2020-12-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding. Proc.Natl.Acad.Sci.USA, 117, 2020
6U4K	Human talin2 residues 1-403 分子名称: Talin-2 著者 Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K. 登録日 2019-08-26 公開日 2020-07-08 最終更新日 2020-09-23 実験手法 X-RAY DIFFRACTION (2.555 Å) 主引用文献 A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020
6R9T	Cryo-EM structure of autoinhibited human talin-1 分子名称: Talin-1 著者 Dedden, D, Schumacher, S, Zacharias, M, Biertumpfel, C, Mizuno, N. 登録日 2019-04-04 公開日 2019-10-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 The Architecture of Talin1 Reveals an Autoinhibition Mechanism. Cell, 179, 2019
6MFS	Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2) 分子名称: PHOSPHATE ION, Talin-1 fusion, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Izard, T, Chinthalapudi, K, Rangarajan, E.S. 登録日 2018-09-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5XBF	Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3 分子名称: ACETATE ION, D-MALATE, GLYCEROL, ... 著者 Li, J, He, Y, Weck, W.L, Lu, Q, Tyska, M.J, Zhang, M. 登録日 2017-03-17 公開日 2017-05-17 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5MV9	Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV8	Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV7	Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain 分子名称: SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb 著者 Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-15 公開日 2017-07-05 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5U1M	Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor 分子名称: Insulin receptor, Insulin receptor substrate 1 著者 Eck, M.J, Dhe-Paganon, S. 登録日 2016-11-28 公開日 2017-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Nat Commun, 8, 2017
5EJS	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain, mutant 1 分子名称: Myosin-I heavy chain 著者 Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2015-11-02 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
5EJR	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain 分子名称: 1,2-ETHANEDIOL, Myosin-I heavy chain 著者 Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Clause, J, Titus, M.A, Houdusse, A. 登録日 2015-11-02 公開日 2016-07-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
2MWN	Talin-F3 / RIAM N-terminal Peptide complex 分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1 著者 Yang, J, Zhu, L, Zhang, H, Hirbawi, J, Fukuda, K, Dwivedi, P, Liu, J, Byzova, T, Plow, E.F, Wu, J, Qin, J. 登録日 2014-11-13 公開日 2014-12-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion. Nat Commun, 5, 2014
2MFQ	NMR solution structures of FRS2a PTB domain with neurotrophin receptor TrkB 分子名称: BDNF/NT-3 growth factors receptor, Fibroblast growth factor receptor substrate 2 著者 Zeng, L, Zhou, M. 登録日 2013-10-18 公開日 2014-03-05 最終更新日 2014-06-25 実験手法 SOLUTION NMR 主引用文献 Structural insights into FRS2 alpha PTB domain recognition by neurotrophin receptor TrkB. Proteins, 82, 2014
4F7G	Crystal structure of talin autoinhibition complex 分子名称: Talin-1 著者 Song, X, Qin, J, Ye, S, Zhang, R. 登録日 2012-05-16 公開日 2012-07-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion. Cell Res., 22, 2012
3ML4	Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region 分子名称: Muscle, skeletal receptor tyrosine-protein kinase, Protein Dok-7 著者 Bergamin, E, Hubbard, S.R. 登録日 2010-04-16 公開日 2010-07-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization. Mol.Cell, 39, 2010
2KUQ	Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK 分子名称: Fibroblast growth factor receptor substrate 3,LINKER,ALK tyrosine kinase receptor 著者 Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2010-02-24 公開日 2010-05-26 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2 J.Struct.Funct.Genom., 11, 2010
2KUP	Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK 分子名称: 19-residue peptide from ALK tyrosine kinase receptor, Fibroblast growth factor receptor substrate 3 著者 Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2010-02-24 公開日 2010-05-26 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2 J.Struct.Funct.Genom., 11, 2010
3IVF	Crystal structure of the talin head FERM domain 分子名称: Talin-1 著者 Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. 登録日 2009-09-01 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The Structure of the talin head reveals a novel extended conformation of the FERM domain Structure, 18, 2010

 

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