6VGU

Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin

Summary for 6VGU

• Entry DOI: 10.2210/pdb6vgu/pdb
• Related: 3ivf
• Descriptor: Integrin beta-3,Talin-1 (2 entities in total)
• Functional Keywords: talin, ferm-fold, nply motif, integrin, signaling protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 1
• Total formula weight: 50382.75

Authors

Zhang, P.,Sun, Y.,Wu, J. (deposition date: 2020-01-09, release date: 2020-12-16, Last modification date: 2023-10-11)

• Primary citation: Zhang, P.,Azizi, L.,Kukkurainen, S.,Gao, T.,Baikoghli, M.,Jacquier, M.C.,Sun, Y.,Maatta, J.A.E.,Cheng, R.H.,Wehrle-Haller, B.,Hytonen, V.P.,Wu, J.; Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.; Proc.Natl.Acad.Sci.USA, 117:32402-32412, 2020; PubMed: 33288722; DOI: 10.1073/pnas.2014583117

Experimental method

X-RAY DIFFRACTION (2.78 Å)