8FSE

Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain

Summary for 8FSE

• Entry DOI: 10.2210/pdb8fse/pdb
• Descriptor: Integrin beta-2,Talin-1 (2 entities in total)
• Functional Keywords: integrin, beta-2, talin, ferm, complex, cell adhesion
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 94812.93

Authors

Wu, J.,Gao, T. (deposition date: 2023-01-09, release date: 2024-07-03)

• Primary citation: Gao, T.,Kabir, S.,Wu, J.; Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation; Biorxiv, 2024; DOI: 10.1101/2024.05.28.596271

Experimental method

X-RAY DIFFRACTION (1.9 Å)