8FSE

Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Integrin beta-2,Talin-1	polymer	411	47406.5	2	UniProt (P11835) UniProt (P26039) Pfam (PF16511) Pfam (PF00373) Pfam (PF02174) In PDB	Mus musculus (house mouse)	Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta,Complement receptor C3 subunit beta
2		water	water		18.0	984	Chemie (HOH)

Sequence modifications

A, B: -9 - 0 (UniProt: P11835)

PDB	External Database	Details
Met -10	-	initiating methionine

A, B: 1 - 430 (UniProt: P26039)

PDB	External Database	Details
-	Asp 139	deletion
-	Glu 140	deletion
-	Gly 141	deletion
-	Thr 142	deletion
-	Gly 143	deletion
-	Thr 144	deletion
-	Leu 145	deletion
-	Arg 146	deletion
-	Lys 147	deletion
-	Asp 148	deletion
-	Lys 149	deletion
-	Thr 150	deletion
-	Leu 151	deletion
-	Leu 152	deletion
-	Arg 153	deletion
-	Asp 154	deletion
-	Glu 155	deletion
-	Lys 156	deletion
-	Lys 157	deletion
-	Met 158	deletion
-	Glu 159	deletion
-	Lys 160	deletion
-	Leu 161	deletion
-	Lys 162	deletion
-	Gln 163	deletion
-	Lys 164	deletion
-	Leu 165	deletion
-	His 166	deletion
-	Thr 167	deletion
-	Asp 168	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94812.9
All*	Total formula weight	94812.9

*Water molecules are not included.