PDB: 62 件ウェブページステータス検索Chemie searchBIRD

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6WO1	Hybrid acetohydroxyacid synthase complex structure with Cryptococcus neoformans AHAS catalytic subunit and Saccharomyces cerevisiae AHAS regulatory subunit 分子名称: 2-methylpyrimidin-4-amine, Acetohydroxyacid synthase catalytic subunit, Acetohydroxyacid synthase regulatory subunit, ... 著者 Guddat, L.W, Lonhienne, T. 登録日 2020-04-23 公開日 2020-07-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
6VZ8	Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound 分子名称: Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ... 著者 Guddat, L.W, Low, Y.S. 登録日 2020-02-27 公開日 2020-07-15 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
6LPI	Crystal Structure of AHAS holo-enzyme 分子名称: Acetolactate synthase isozyme 1 large subunit, Acetolactate synthase isozyme 1 small subunit, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Zhang, Y, Yang, X, Xi, Z, Shen, Y. 登録日 2020-01-10 公開日 2020-11-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.849 Å) 主引用文献 Molecular architecture of the acetohydroxyacid synthase holoenzyme. Biochem.J., 477, 2020
6U9D	Saccharomyces cerevisiae acetohydroxyacid synthase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Acetolactate synthase catalytic subunit, mitochondrial, ... 著者 Guddat, L.W, Lonhienne, T. 登録日 2019-09-08 公開日 2020-07-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.194 Å) 主引用文献 Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
6U9H	Arabidopsis thaliana acetohydroxyacid synthase complex 分子名称: Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ... 著者 Guddat, L.W, Low, Y.S, Rao, Z. 登録日 2019-09-08 公開日 2020-07-15 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
6U60	Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD and L-tyrosine 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, Prephenate dehydrogenase, ... 著者 Shabalin, I.G, Hou, J, Kutner, J, Grimshaw, S, Christendat, D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-08-28 公開日 2019-09-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
6N1K	Full-length human phenylalanine hydroxylase (PAH) in the resting state 分子名称: CHLORIDE ION, FE (III) ION, Phenylalanine-4-hydroxylase 著者 Arturo, E.C, Jaffe, E.K. 登録日 2018-11-08 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.057 Å) 主引用文献 Biophysical characterization of full-length human phenylalanine hydroxylase provides a deeper understanding of its quaternary structure equilibrium. J.Biol.Chem., 294, 2019
6HYC	The structure of full-length human phenylalanine hydroxylase in complex with the cofactor and negative regulator tetrahydrobiopterin 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, Phenylalanine-4-hydroxylase 著者 Alcorlo Pages, M, Flydal, I.M. 登録日 2018-10-19 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. Proc.Natl.Acad.Sci.USA, 116, 2019
6HTQ	Stringent response control by a bifunctional RelA enzyme in the presence and absence of the ribosome 分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Wilson, D.N, Abdelshahid, M. 登録日 2018-10-04 公開日 2019-10-23 最終更新日 2020-09-30 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel. Cell Rep, 32, 2020
6HPO	Crystallographic structure of the catalytic domain of Human Phenylalanine Hydroxylase (hPAH CD) in complex with iron at 1.6 Angstrom 分子名称: FE (III) ION, Phenylalanine-4-hydroxylase 著者 Alcorlo Pages, M, Innselset Flydal, M. 登録日 2018-09-21 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. Proc.Natl.Acad.Sci.USA, 116, 2019
6DZS	Mycobacterial homoserine dehydrogenase ThrA in complex with NADP 分子名称: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Chaton, C.T, Rodriguez, E.S, Korotkov, K.V. 登録日 2018-07-05 公開日 2018-07-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structure of mycobacterial homoserine dehydrogenase ThrA To be Published
5YUM	Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback inhibition of AHASs 分子名称: Acetolactate synthase isozyme 1 small subunit, COBALT (II) ION, ISOLEUCINE 著者 Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. 登録日 2017-11-22 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.432 Å) 主引用文献 Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
5YPY	Crystal structure of IlvN. Val-1c 分子名称: Acetolactate synthase isozyme 1 small subunit, VALINE 著者 Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. 登録日 2017-11-04 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.966 Å) 主引用文献 Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
5YPW	Crystal structure of IlvN.Val-1b 分子名称: Acetolactate synthase isozyme 1 small subunit, VALINE 著者 Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. 登録日 2017-11-03 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
5YPP	Crystal structure of IlvN.Val-1a 分子名称: ACETATE ION, Acetolactate synthase isozyme 1 small subunit, DI(HYDROXYETHYL)ETHER, ... 著者 Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. 登録日 2017-11-02 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
5YEI	Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase 分子名称: Aspartokinase, GLYCEROL, LYSINE, ... 著者 Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R. 登録日 2017-09-17 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase. Biochem.J., 475, 2018
5V0S	Crystal structure of the ACT domain of prephenate dehydrogenase tyrA from Bacillus anthracis 分子名称: CALCIUM ION, Prephenate dehydrogenase, SULFATE ION 著者 Shabalin, I.G, Hou, J, Cymborowski, M.T, Otwinowski, Z, Kwon, K, Christendat, D, Gritsunov, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-28 公開日 2017-03-08 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
5UYY	Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine 分子名称: Prephenate dehydrogenase, TYROSINE 著者 Shabalin, I.G, Hou, J, Cymborowski, M.T, Kwon, K, Christendat, D, Gritsunov, A.O, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-24 公開日 2017-03-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
5FGJ	Structure of tetrameric rat phenylalanine hydroxylase, residues 1-453 分子名称: FE (III) ION, MAGNESIUM ION, Phenylalanine-4-hydroxylase 著者 Taylor, A.B, Roberts, K.M, Fitzpatrick, P.F. 登録日 2015-12-20 公開日 2016-05-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering. J.Am.Chem.Soc., 138, 2016
5EGQ	Structure of tetrameric rat phenylalanine hydroxylase mutant R270K, residues 25-453 分子名称: Phenylalanine-4-hydroxylase, SULFATE ION 著者 Taylor, A.B, Khan, C.A, Fitzpatrick, P.F. 登録日 2015-10-27 公開日 2016-05-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering. J.Am.Chem.Soc., 138, 2016
5FII	Structure of a human aspartate kinase, chorismate mutase and TyrA domain. 分子名称: PHENYLALANINE, PHENYLALANINE-4-HYDROXYLASE 著者 Patel, D, Kopec, J, Shrestha, L, Fitzpatrick, F, Pinkas, D, Chaikuad, A, Dixon-Clarke, S, McCorvie, T.J, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. 登録日 2015-09-25 公開日 2016-03-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Ligand-Dependent Dimerization of Phenylalanine Hydroxylase Regulatory Domain. Sci.Rep., 6, 2016
5DEN	The First Structure of a Full-Length Mammalian Phenylalanine Hydroxylase Reveals the Architecture of an Auto-inhibited Tetramer 分子名称: FE (III) ION, Phenylalanine-4-hydroxylase 著者 Arturo, E.C, Loll, P.J, Jaffe, E.K. 登録日 2015-08-25 公開日 2016-02-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer. Proc.Natl.Acad.Sci.USA, 113, 2016
3W7B	Crystal structure of formyltetrahydrofolate deformylase from Thermus thermophilus HB8 分子名称: Formyltetrahydrofolate deformylase 著者 Sampei, G, Yanagida, Y, Ogata, N, Kusano, M, Terao, K, Kawai, H, Fukai, Y, Kanagawa, M, Inoue, Y, Baba, S, Kawai, G. 登録日 2013-02-28 公開日 2014-01-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structures and reaction mechanisms of the two related enzymes, PurN and PurU J.Biochem., 154, 2013
4GO7	The regulatory subunit of aspartate kinase in complex with threonine from Mycobacterium tuberculosis 分子名称: Aspartokinase, THREONINE 著者 Yang, Q, Li, X. 登録日 2012-08-19 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis. Protein Cell, 2, 2011
4GO5	The regulatory subunit of aspartate kinase from Mycobacterium tuberculosis 分子名称: Aspartokinase 著者 Yang, Q, Li, X. 登録日 2012-08-18 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis. Protein Cell, 2, 2011

 

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