2J6W
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![BU of 2j6w by Molmil](/molmil-images/mine/2j6w) | R164N mutant of the RUNX1 Runt domain | 分子名称: | CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | 著者 | Grembecka, J, Zhe, L, Lukasik, S.M, Liu, Y, Bielnicka, I, Bushweller, J.H, Speck, N.A. | 登録日 | 2006-10-04 | 公開日 | 2007-10-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation. J.Mol.Biol., 364, 2006
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1LJM
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![BU of 1ljm by Molmil](/molmil-images/mine/1ljm) | DNA recognition is mediated by conformational transition and by DNA bending | 分子名称: | CHLORIDE ION, RUNX1 transcription factor | 著者 | Bartfeld, D, Shimon, L, Couture, G.C, Rabinovich, D, Frolow, F, Levanon, D, Groner, Y, Shakked, Z. | 登録日 | 2002-04-22 | 公開日 | 2002-11-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | DNA Recognition by the RUNX1 Transcription Factor Is Mediated by an Allosteric Transition in the RUNT Domain and by DNA Bending. Structure, 10
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1HJC
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![BU of 1hjc by Molmil](/molmil-images/mine/1hjc) | |
1EAQ
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![BU of 1eaq by Molmil](/molmil-images/mine/1eaq) | The RUNX1 Runt domain at 1.25A resolution: A structural switch and specifically bound chloride ions modulate DNA binding | 分子名称: | CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | 著者 | Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H. | 登録日 | 2001-07-14 | 公開日 | 2002-09-12 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding J.Mol.Biol., 322, 2002
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1EAN
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![BU of 1ean by Molmil](/molmil-images/mine/1ean) | THE RUNX1 Runt domain at 1.70A resolution: A structural switch and specifically bound chloride ions modulate DNA binding | 分子名称: | CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | 著者 | Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H. | 登録日 | 2001-07-13 | 公開日 | 2002-09-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding J.Mol.Biol., 322, 2002
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1CMO
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![BU of 1cmo by Molmil](/molmil-images/mine/1cmo) | IMMUNOGLOBULIN MOTIF DNA-RECOGNITION AND HETERODIMERIZATION FOR THE PEBP2/CBF RUNT-DOMAIN | 分子名称: | POLYOMAVIRUS ENHANCER BINDING PROTEIN 2 | 著者 | Nagata, T, Gupta, V, Sorce, D, Kim, W.Y, Sali, A, Chait, B.T, Shigesada, K, Ito, Y, Werner, M.H. | 登録日 | 1999-05-11 | 公開日 | 2000-01-05 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain. Nat.Struct.Biol., 6, 1999
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1CO1
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![BU of 1co1 by Molmil](/molmil-images/mine/1co1) | FOLD OF THE CBFA | 分子名称: | CORE BINDING FACTOR ALPHA | 著者 | Berardi, M.J, Bushweller, J.H. | 登録日 | 1999-05-31 | 公開日 | 2000-06-07 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains. Structure Fold.Des., 7, 1999
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1EAO
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![BU of 1eao by Molmil](/molmil-images/mine/1eao) | THE RUNX1 Runt domain at 1.4A resolution: a structural switch and specifically bound chloride ions modulate DNA binding | 分子名称: | BROMIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | 著者 | Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T.H, Grundstrom, T, Sauer, U.H. | 登録日 | 2001-07-14 | 公開日 | 2002-09-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The Runx1 Runt Domain at 1.25A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding J.Mol.Biol., 322, 2002
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1H9D
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![BU of 1h9d by Molmil](/molmil-images/mine/1h9d) | Aml1/cbf-beta/dna complex | 分子名称: | CORE-BINDING FACTOR ALPHA SUBUNIT1, CORE-BINDING FACTOR CBF-BETA, DNA (5'-(*CP*AP*AP*CP*CP*GP*CP*AP*AP*C)-3'), ... | 著者 | Bravo, J, Warren, A.J. | 登録日 | 2001-03-07 | 公開日 | 2001-03-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Leukemia-Associated Aml1 (Runx1)-Cbfbeta Complex Functions as a DNA-Induced Molecular Clamp Nat.Struct.Biol., 8, 2001
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1HJB
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1IO4
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![BU of 1io4 by Molmil](/molmil-images/mine/1io4) | |
1E50
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![BU of 1e50 by Molmil](/molmil-images/mine/1e50) | AML1/CBFbeta complex | 分子名称: | CORE-BINDING FACTOR ALPHA SUBUNIT, CORE-BINDING FACTOR CBF-BETA | 著者 | Warren, A.J, Bravo, J, Williams, R.L, Rabbits, T.H. | 登録日 | 2000-07-13 | 公開日 | 2001-07-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis for the Heterodimeric Interaction between the Acute Leukaemia-Associated Transcription Factors Aml1 and Cbfbeta Embo J., 19, 2000
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3WTU
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![BU of 3wtu by Molmil](/molmil-images/mine/3wtu) | Crystal structure of the complex comprised of ETS1 (V170A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WU1
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![BU of 3wu1 by Molmil](/molmil-images/mine/3wu1) | Crystal structure of the ETS1-RUNX1-DNA ternary complex | 分子名称: | DNA (5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), Protein C-ets-1, ... | 著者 | Tahirov, T.H, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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4L0Y
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![BU of 4l0y by Molmil](/molmil-images/mine/4l0y) | |
4L18
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![BU of 4l18 by Molmil](/molmil-images/mine/4l18) | |
4L0Z
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6VGD
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6VGG
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![BU of 6vgg by Molmil](/molmil-images/mine/6vgg) | Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... | 著者 | Hou, C, Rohr, J, Tsodikov, O.V. | 登録日 | 2020-01-08 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.31 Å) | 主引用文献 | Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
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6VGE
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![BU of 6vge by Molmil](/molmil-images/mine/6vge) | Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... | 著者 | Hou, C, Tsodikov, O.V. | 登録日 | 2020-01-07 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.25 Å) | 主引用文献 | Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
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6VG8
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3WTW
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![BU of 3wtw by Molmil](/molmil-images/mine/3wtw) | Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WTY
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![BU of 3wty by Molmil](/molmil-images/mine/3wty) | Crystal structure of the complex comprised of ETS1(G333P), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WTX
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![BU of 3wtx by Molmil](/molmil-images/mine/3wtx) | Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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3WTV
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![BU of 3wtv by Molmil](/molmil-images/mine/3wtv) | Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... | 著者 | Shiina, M, Hamada, K, Ogata, K. | 登録日 | 2014-04-21 | 公開日 | 2014-08-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
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