5IZA
| Protein-protein interaction | 分子名称: | ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2, Adenomatous polyposis coli protein | 著者 | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | 登録日 | 2016-03-25 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
|
|
3TT9
| Crystal structure of the stable degradation fragment of human plakophilin 2 isoform a (PKP2a) C752R variant | 分子名称: | GLYCEROL, Plakophilin-2 | 著者 | Schuetz, A, Roske, Y, Gerull, B, Heinemann, U. | 登録日 | 2011-09-14 | 公開日 | 2012-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations. Circ Cardiovasc Genet, 5, 2012
|
|
3NMW
| Crystal structure of armadillo repeats domain of APC | 分子名称: | APC variant protein, SULFATE ION | 著者 | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | 登録日 | 2010-06-22 | 公開日 | 2011-07-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
|
|
6BW9
| Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1 | 分子名称: | Importin subunit alpha-3, Protein W | 著者 | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | 登録日 | 2017-12-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
|
|
4UAF
| |
5CTT
| |
6IUA
| |
4YK6
| Crystal structure of APC-ARM in complexed with Amer1-A4 | 分子名称: | APC membrane recruitment protein 1, Adenomatous polyposis coli protein | 著者 | Zhang, Z, Xiao, Y, Wu, G. | 登録日 | 2015-03-04 | 公開日 | 2016-03-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners Cell Discov, 1, 2015
|
|
6K06
| Crystal structure of Importin-alpha and phosphomimetic GM130 | 分子名称: | Importin subunit alpha-1, Peptide from Golgin subfamily A member 2 | 著者 | Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. | 登録日 | 2019-05-05 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10, 2019
|
|
4WV6
| |
4RXH
| |
5Z8H
| |
8HE0
| |
4YI0
| |
7AFW
| Beta-Catenin in complex with compound 6 | 分子名称: | 3-[(2~{R})-4-methyl-5-oxidanylidene-2,3-dihydro-1,4-benzoxazepin-2-yl]benzenecarbonitrile, Catenin beta-1 | 著者 | Boettcher, J, Kessler, D. | 登録日 | 2020-09-21 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.814 Å) | 主引用文献 | Getting a Grip on the Undrugged: Targeting beta-Catenin with Fragment-Based Methods. Chemmedchem, 16, 2021
|
|
7RG1
| Importin alpha2 in complex with MERS ORF4B H26A mutant | 分子名称: | Importin subunit alpha-1, ORF4b | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Importin alpha2 in complex with MERS ORF4B NLS H26A mutant To Be Published
|
|
4MZ6
| Structure of importin-alpha: dUTPase S11E NLS mutant complex | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | 登録日 | 2013-09-29 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr.,Sect.D, 69, 2013
|
|
4EV8
| |
8FUA
| Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein NLS1 | 分子名称: | Importin subunit alpha-1, Matrix protein | 著者 | Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. | 登録日 | 2023-01-17 | 公開日 | 2023-02-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023
|
|
8QXX
| HCMV DNA polymerase processivity factor UL44 phosphorylated NLS 410-433 bound to mouse importin alpha 2 | 分子名称: | DNA polymerase processivity factor, Importin subunit alpha-1 | 著者 | Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. | 登録日 | 2023-10-25 | 公開日 | 2023-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. Febs Lett., 598, 2024
|
|
8HKW
| |
8HE3
| |
5D5K
| |
5UMZ
| |
6IU7
| |