7AFW
Beta-Catenin in complex with compound 6
Summary for 7AFW
Entry DOI | 10.2210/pdb7afw/pdb |
Descriptor | Catenin beta-1, 3-[(2~{R})-4-methyl-5-oxidanylidene-2,3-dihydro-1,4-benzoxazepin-2-yl]benzenecarbonitrile (3 entities in total) |
Functional Keywords | fragment, oncoprotein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 18454.48 |
Authors | Boettcher, J.,Kessler, D. (deposition date: 2020-09-21, release date: 2020-12-16, Last modification date: 2024-01-31) |
Primary citation | Kessler, D.,Mayer, M.,Zahn, S.K.,Zeeb, M.,Wohrle, S.,Bergner, A.,Bruchhaus, J.,Ciftci, T.,Dahmann, G.,Dettling, M.,Dobel, S.,Fuchs, J.E.,Geist, L.,Hela, W.,Kofink, C.,Kousek, R.,Moser, F.,Puchner, T.,Rumpel, K.,Scharnweber, M.,Werni, P.,Wolkerstorfer, B.,Breitsprecher, D.,Baaske, P.,Pearson, M.,McConnell, D.B.,Bottcher, J. Getting a Grip on the Undrugged: Targeting beta-Catenin with Fragment-Based Methods. Chemmedchem, 16:1420-1424, 2021 Cited by PubMed: 33275320DOI: 10.1002/cmdc.202000839 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.814 Å) |
Structure validation
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