PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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6WTY	Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 253245 分子名称: 253245 Fab heavy chain, 253245 Fab light chain, reticulocyte binding protein 2b 著者 Chan, L.J, Dietrich, M.H, Tham, W.H. 登録日 2020-05-04 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.481 Å) 主引用文献 Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b. Nat Commun, 12, 2021
6WTV	Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 258259 分子名称: 258259 Fab heavy chain, 258259 Fab light chain, reticulocyte binding protein 2b 著者 Chan, L.J, Dietrich, M.H, Tham, W.H. 登録日 2020-05-04 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b. Nat Commun, 12, 2021
8CXC	Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics 分子名称: 3F2 Antibody heavy chain, 3F2 Antibody light chain, Mesothelin, ... 著者 Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. 登録日 2022-05-20 公開日 2023-06-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (4.31 Å) 主引用文献 Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
8CYH	Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A12 antibody heavy chain, A12 antibody light chain, ... 著者 Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. 登録日 2022-05-23 公開日 2023-06-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
7EO0	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY C4 分子名称: Ig heavy chain variable region, Ig lamda chain variable region, O/TIBET/99 VP1, ... 著者 He, Y, Li, K. 登録日 2021-04-21 公開日 2021-08-18 最終更新日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Two Cross-Protective Antigen Sites on Foot-and-Mouth Disease Virus Serotype O Structurally Revealed by Broadly Neutralizing Antibodies from Cattle. J.Virol., 95, 2021
7JMO	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-04 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-04 heavy chain, COVA2-04 light chain, ... 著者 Wu, N.C, Yuan, M, Liu, H, Zhu, X, Wilson, I.A. 登録日 2020-08-02 公開日 2020-08-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.359 Å) 主引用文献 An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain. Cell Rep, 33, 2020
7C01	Molecular basis for a potent human neutralizing antibody targeting SARS-CoV-2 RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CB6 heavy chain, CB6 light chain, ... 著者 Shi, R, Qi, J, Wang, Q, Gao, F.G, Yan, J. 登録日 2020-04-29 公開日 2020-05-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2. Nature, 584, 2020
7JMP	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-39 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-39 heavy chain, COVA2-39 light chain, ... 著者 Wu, N.C, Yuan, M, Liu, H, Zhu, X, Wilson, I.A. 登録日 2020-08-02 公開日 2020-08-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.712 Å) 主引用文献 An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain. Cell Rep, 33, 2020
4FQQ	Crystal Structure of Germline Antibody PGT121-GL Fab 分子名称: Fab heavy chain, Fab light chain, SODIUM ION 著者 Scharf, L, Bjorkman, P.J. 登録日 2012-06-25 公開日 2012-11-14 最終更新日 2021-05-19 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proc.Natl.Acad.Sci.USA, 109, 2012
6MNR	Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide 分子名称: 1,2-ETHANEDIOL, Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, ... 著者 Nicely, N.I. 登録日 2018-10-02 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. Nat Commun, 10, 2019
6MNQ	Rhesus macaque anti-HIV V3 antibody DH727.2 with gp120 V3 ZAM18 peptide 分子名称: 1,2-ETHANEDIOL, Ab DH727.2 heavy chain Fab fragment, Ab DH727.2 light chain, ... 著者 Nicely, N.I. 登録日 2018-10-02 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.804 Å) 主引用文献 Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. Nat Commun, 10, 2019
7KHF	CryoEM structure of LILRB1 D3D4 domain-inserted antibody MDB1 Fab in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MDB1 Fab heavy chain, ... 著者 Xu, K, Kwong, P.D. 登録日 2020-10-21 公開日 2021-03-31 最終更新日 2021-05-05 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural basis of malaria RIFIN binding by LILRB1-containing antibodies. Nature, 592, 2021
4OTX	Structure of the anti-Francisella tularensis O-antigen antibody N203 Fab fragment 分子名称: AZIDE ION, CHLORIDE ION, N203 heavy chain, ... 著者 Lu, Z, Rynkiewicz, M.J, Yang, C.-Y, Madico, G, Perkins, H.M, Roche, M.I, Seaton, B.A, Sharon, J. 登録日 2014-02-14 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Functional and Structural Characterization of Francisella tularensis O-Antigen Antibodies at the Low End of Antigen Reactivity. Monoclon Antib Immunodiagn Immunother, 33, 2014
6MNS	Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide 分子名称: Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, Envelope glylcoprotein, ... 著者 Nicely, N.I. 登録日 2018-10-02 公開日 2019-07-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. Nat Commun, 10, 2019
7VNB	Crystal structure of the SARS-CoV-2 RBD in complex with a human single domain antibody n3113 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, n3113 著者 Yang, Z, Wang, Y, Kong, Y, Jin, Y, Wu, Y, Ying, T. 登録日 2021-10-10 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants. Signal Transduct Target Ther, 6, 2021
7EAN	immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 6D6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 cross-neutralizing mAb 6D6, Light chain of SARS-CoV-2 cross-neutralizing mAb 6D6, ... 著者 Li, T.T, Gu, Y, Li, S.W. 登録日 2021-03-07 公開日 2021-03-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants. Nat Commun, 12, 2021
7MM0	Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B1-182.1 Fab heavy chain, ... 著者 Zhou, T, Tsybovsky, T, Kwong, P.D. 登録日 2021-04-29 公開日 2021-07-28 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021
7MEM	CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 045-09 2B05, ... 著者 Han, J, Ward, A. 登録日 2021-04-06 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med, 13, 2021
7KD0	Ricin bound to VHH antibody V2C11 分子名称: 1,2-ETHANEDIOL, Anti-RON nanobody, CHLORIDE ION, ... 著者 Rudolph, M.J. 登録日 2020-10-07 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.768 Å) 主引用文献 Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface. J.Mol.Biol., 433, 2021
7W7Q	Crystal structure of 1F11S antibody(ScFv) 分子名称: 1F11S antibody 著者 Kim, B.-W, Park, J, Woo, J, Lee, W.-K. 登録日 2021-12-06 公開日 2022-12-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structure of 1F11S antibody(ScFv) To Be Published
7WOS	The state 3 of Omicron Spike with bispecific antibody FD01 分子名称: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... 著者 Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. 登録日 2022-01-22 公開日 2022-11-30 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
7WOQ	The state 1 of Omicron Spike with bispecific antibody FD01 分子名称: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. 登録日 2022-01-22 公開日 2022-11-30 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
6CHB	Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and IOMA 分子名称: BG18 Heavy Chain, BG18 Light Chain, Envelope glycoprotein gp120, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2018-02-22 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (6.801 Å) 主引用文献 Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope. Nat Commun, 9, 2018
5YSL	Crystal structure of antibody 1H1 Fab 分子名称: 1H1 heavy chain, 1H1 light chain 著者 Hu, X.L, Yang, F.L. 登録日 2017-11-14 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design. PLoS Pathog., 13, 2017
7LM9	Crystal structure of SARS-CoV spike protein receptor-binding domain in complex with a cross-neutralizing antibody CV38-142 Fab isolated from COVID-19 patient 分子名称: 1,2-ETHANEDIOL, CV38-142 Fab heavy chain, CV38-142 Fab light chain, ... 著者 Liu, H, Yuan, M, Zhu, X, Wilson, I.A. 登録日 2021-02-05 公開日 2021-03-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host Microbe, 29, 2021

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