8GIX
 
 | | Chaetomium thermophilum Hir3 | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, Histone transcription regulator 3 homolog | | 著者 | Szurgot, M.R, van Eeuwen, T, Kim, H.J, Marmorstein, R. | | 登録日 | 2023-03-14 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the Hir histone chaperone complex.
Mol.Cell, 84, 2024
|
|
1AEW
 | | L-CHAIN HORSE APOFERRITIN | | 分子名称: | CADMIUM ION, FERRITIN | | 著者 | Hempstead, P.D, Yewdall, S.J, Lawson, D.M, Harrison, P.M, Artymiuk, P.J. | | 登録日 | 1997-02-26 | | 公開日 | 1997-09-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Comparison of the three-dimensional structures of recombinant human H and horse L ferritins at high resolution.
J.Mol.Biol., 268, 1997
|
|
3VVV
 | | Skich domain of NDP52 | | 分子名称: | Calcium-binding and coiled-coil domain-containing protein 2 | | 著者 | Akutsu, M, Muhlinen, N.V, Randow, F, Komander, D. | | 登録日 | 2012-07-28 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
Mol.Cell, 48, 2012
|
|
6R2N
 | | Crystal structure of KlGlk1 glucokinase from Kluyveromyces lactis | | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, Glucokinase-1 | | 著者 | Zak, K, Wator, E, Grudnik, P. | | 登録日 | 2019-03-18 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Crystal Structure of Kluyveromyces lactis Glucokinase ( Kl Glk1).
Int J Mol Sci, 20, 2019
|
|
8F49
 | |
6R6F
 | | Crystal structure of human carbonic anhydrase isozyme II with 4-chloro-2-cyclohexylsulfanyl-N-(2-hydroxyethyl)-5-sulfamoyl-benzamide | | 分子名称: | 4-chloranyl-2-cyclohexylsulfanyl-~{N}-(2-hydroxyethyl)-5-sulfamoyl-benzamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2019-03-27 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
|
|
3M0I
 | | Human Aldose Reductase mutant T113V in complex with Zopolrestat | | 分子名称: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Koch, C, Heine, A, Klebe, G. | | 登録日 | 2010-03-03 | | 公開日 | 2011-03-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Ligand-induced fit affects binding modes and provokes changes in crystal packing of aldose reductase
Biochim.Biophys.Acta, 1810, 2011
|
|
3M96
 | | Crystal structure of human carbonic anhydrase isozyme II with 5-{[(5-bromo-1H-benzimidazol-2-yl)sulfanyl]acetyl}-2-chlorobenzenesulfonamide | | 分子名称: | 5-{[(5-bromo-1H-benzimidazol-2-yl)sulfanyl]acetyl}-2-chlorobenzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Grazulis, S, Manakova, E, Golovenko, D. | | 登録日 | 2010-03-20 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII.
Bioorg.Med.Chem., 18, 2010
|
|
3V83
 | | The 2.1 angstrom crystal structure of diferric human transferrin | | 分子名称: | BICARBONATE ION, FE (III) ION, HEXAETHYLENE GLYCOL, ... | | 著者 | Noinaj, N, Steere, A, Mason, A.B, Buchanan, S.K. | | 登録日 | 2011-12-22 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | Structural basis for iron piracy by pathogenic Neisseria.
Nature, 483, 2012
|
|
1QWO
 | | Crystal structure of a phosphorylated phytase from Aspergillus fumigatus, revealing the structural basis for its heat resilience and catalytic pathway | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, phytase | | 著者 | Xiang, T, Liu, Q, Deacon, A.M, Koshy, M, Kriksunov, I.A, Lei, X.G, Hao, Q, Thiel, D.J. | | 登録日 | 2003-09-03 | | 公開日 | 2004-06-01 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of a Heat-resilient Phytase from Aspergillus fumigatus, Carrying a Phosphorylated Histidine
J.Mol.Biol., 339, 2004
|
|
2F2K
 | | Aldose reductase tertiary complex with NADPH and DEG | | 分子名称: | Aldose reductase, GAMMA-GLUTAMYL-S-(1,2-DICARBOXYETHYL)CYSTEINYLGLYCINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Singh, R, White, M.A, Ramana, K.V, Petrash, J.M, Watowich, S.J, Bhatnagar, A, Srivastava, S.K. | | 登録日 | 2005-11-17 | | 公開日 | 2006-05-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structure of a glutathione conjugate bound to the active site of aldose reductase.
Proteins, 64, 2006
|
|
1Q8T
 | | The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 | | 分子名称: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | | 著者 | Breitenlechner, C, Gassel, M, Hidaka, H, Kinzel, V, Huber, R, Engh, R.A, Bossemeyer, D. | | 登録日 | 2003-08-22 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
Structure, 11, 2003
|
|
2BTZ
 | | crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands | | 分子名称: | PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2 | | 著者 | Knoechel, T.R, Tucker, A.D, Robinson, C.M, Phillips, C, Taylor, W, Bungay, P.J, Kasten, S.A, Roche, T.E, Brown, D.G. | | 登録日 | 2005-06-08 | | 公開日 | 2006-02-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands.
Biochemistry, 45, 2006
|
|
3PIN
 | | Crystal structure of Mxr1 from Saccharomyces cerevisiae in complex with Trx2 | | 分子名称: | Peptide methionine sulfoxide reductase, Thioredoxin-2 | | 著者 | Ma, X.X, Guo, P.C, Shi, W.W, Luo, M, Tan, X.F, Chen, Y, Zhou, C.Z. | | 登録日 | 2010-11-07 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1
J.Biol.Chem., 286, 2011
|
|
1ALA
 | |
3G5U
 | | Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding | | 分子名称: | MERCURY (II) ION, Multidrug resistance protein 1a | | 著者 | Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. | | 登録日 | 2009-02-05 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
|
|
3VXG
 | | Crystal structure of conjugated polyketone reductase C2 from Candida Parapsilosis | | 分子名称: | Conjugated polyketone reductase C2 | | 著者 | Qin, H.-M, Yamamura, A, Miyakawa, T, Maruoka, S, Ohtsuka, J, Nagata, K, Kataoka, M, Shimizu, S, Tanokura, M. | | 登録日 | 2012-09-13 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH binding
Appl.Microbiol.Biotechnol., 98, 2014
|
|
1Q9E
 | | RNase T1 variant with adenine specificity | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Guanyl-specific ribonuclease T1 precursor | | 著者 | Czaja, R, Struhalla, M, Hoeschler, K, Saenger, W, Straeter, N, Hahn, U. | | 登録日 | 2003-08-25 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | RNase T1 Variant RV Cleaves Single-Stranded RNA after Purines Due to Specific Recognition by the Asn46 Side Chain Amide.
Biochemistry, 43, 2004
|
|
4FA8
 | | Multi-pronged modulation of cytokine signaling | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage colony-stimulating factor 1, Secreted protein BARF1, ... | | 著者 | He, X, Shim, A.H. | | 登録日 | 2012-05-21 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2F6J
 | |
4ISP
 | |
6HQX
 | | Human Carbonic Anhydrase II in complex with 4-Ethylbenzenesulfonamide | | 分子名称: | (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-ethylbenzenesulfonamide, Carbonic anhydrase 2, ... | | 著者 | Gloeckner, S, Heine, A, Klebe, G. | | 登録日 | 2018-09-25 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.097 Å) | | 主引用文献 | Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors.
Acs Chem.Biol., 15, 2020
|
|
1HQM
 | | CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K. | | 登録日 | 2000-12-18 | | 公開日 | 2001-02-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
3G8T
 | | Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P | | 分子名称: | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3'), ... | | 著者 | Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D. | | 登録日 | 2009-02-12 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
|
|
4ITO
 | | Human CA II inhibition by novel sulfonamide | | 分子名称: | 4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Aggarwal, M, McKenna, R. | | 登録日 | 2013-01-18 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.162 Å) | | 主引用文献 | Human CA II inhibition by novel sulfonamide
To be Published
|
|
