6HQX
Human Carbonic Anhydrase II in complex with 4-Ethylbenzenesulfonamide
Summary for 6HQX
| Entry DOI | 10.2210/pdb6hqx/pdb |
| Related | 6GDC 6GM9 |
| Descriptor | Carbonic anhydrase 2, ZINC ION, beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | lyase, inhibitor, complex, co2-conversion |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 30980.38 |
| Authors | Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2018-09-25, release date: 2019-10-09, Last modification date: 2024-01-24) |
| Primary citation | Glockner, S.,Ngo, K.,Sager, C.P.,Hufner-Wulsdorf, T.,Heine, A.,Klebe, G. Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors. Acs Chem.Biol., 15:675-685, 2020 Cited by PubMed: 32027480DOI: 10.1021/acschembio.9b00895 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.097 Å) |
Structure validation
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