2F6J

Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state

Summary for 2F6J

Related2F6J
Descriptorbromodomain PHD finger transcription factor, histone H3, N-terminal, ZINC ION, ... (4 entities in total)
Functional Keywordsphd finger; bromo domain; histone tail binding; methylation, transcription
Biological sourceHomo sapiens (human)
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Total number of polymer chains4
Total molecular weight63594.92
Authors
Li, H.,Patel, D.J. (deposition date: 2005-11-29, release date: 2006-07-11, Last modification date: 2011-07-13)
Primary citation
Li, H.,Ilin, S.,Wang, W.,Duncan, E.M.,Wysocka, J.,Allis, C.D.,Patel, D.J.
Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442:91-95, 2006
PubMed: 16728978 (PDB entries with the same primary citation)
DOI: 10.1038/nature04802
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.218702.4%5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution