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3RG3
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BU of 3rg3 by Molmil
Crystal structure of the W5E mutant of human carbonic anhydrase II
分子名称: Carbonic anhydrase 2, ZINC ION
著者Domsic, J.F, Robbins, A.H, McKenna, R.
登録日2011-04-07
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.
Arch.Biochem.Biophys., 516, 2011
4Q06
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BU of 4q06 by Molmil
Crystal structure of chimeric carbonic anhydrase IX with inhibitor
分子名称: 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ...
著者Smirnov, A, Manakova, E, Grazulis, S.
登録日2014-04-01
公開日2015-01-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.
J.Med.Chem., 57, 2014
8CT8
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BU of 8ct8 by Molmil
Crystal structure of Drosophila melanogaster PRL/CBS-pair domain complex
分子名称: IODIDE ION, PRL-1 phosphatase, Unextended protein
著者Fakih, R, Goldstein, R.H, Kozlov, G, Gehring, K.
登録日2022-05-13
公開日2023-03-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver.
J.Biol.Chem., 299, 2023
3RJJ
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BU of 3rjj by Molmil
Ternary complex crystal structure of DNA Polymerase Beta with template 8odG provides insight into mutagenic lesion bypass
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*(8OG)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Batra, V.K, Beard, W.A, Wilson, S.H.
登録日2011-04-15
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binary complex crystal structure of DNA polymerase beta reveals multiple conformations of the templating 8-oxoguanine lesion.
Proc.Natl.Acad.Sci.USA, 109, 2012
1ZN7
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BU of 1zn7 by Molmil
Human Adenine Phosphoribosyltransferase Complexed with PRPP, ADE and R5P
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 5-O-phosphono-alpha-D-ribofuranose, ADENINE, ...
著者Iulek, J, Silva, M, Tomich, C.H.T.P, Thiemann, O.H.
登録日2005-05-11
公開日2006-04-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism
J.Biomol.Struct.Dyn., 25, 2008
4MG5
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BU of 4mg5 by Molmil
Crystal structure of hERa-LBD (Y537S) in complex with chlordecone
分子名称: Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ...
著者Delfosse, V, Grimaldi, M, Bourguet, W.
登録日2013-08-28
公開日2014-09-03
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and functional profiling of environmental ligands for estrogen receptors.
Environ.Health Perspect., 122, 2014
7M14
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BU of 7m14 by Molmil
x-ray structure of cj1430 in the presence of GDP, a GDP-D-glycero-4-keto-D-lyxo-heptose-3,5-epimerase from campylobacter jejuni
分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, SODIUM ION, ...
著者Girardi, N.M, Thoden, J.B, Raushel, F.M, Holden, H.M.
登録日2021-03-12
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biosynthesis of d- glycero -l- gluco -Heptose in the Capsular Polysaccharides of Campylobacter jejuni .
Biochemistry, 60, 2021
4Q8Y
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BU of 4q8y by Molmil
Crystal structure of 2-hydroxyisoquinoline-1(2H)-thione bound to human carbonic anhydrase II
分子名称: 2-hydroxyisoquinoline-1(2H)-thione, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ...
著者Martin, D.P, Cohen, S.M.
登録日2014-04-28
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q95
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BU of 4q95 by Molmil
Crystal structure of HRASLS3/LRAT chimeric protein
分子名称: HEPTANOIC ACID, HRAS-like suppressor 3, Lecithin retinol acyltransferase
著者Golczak, M, Kiser, P.D, Sears, A.E, Palczewski, K.
登録日2014-04-29
公開日2014-10-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3.
Nat.Chem.Biol., 11, 2015
4HN6
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BU of 4hn6 by Molmil
GR DNA Binding Domain R460D/D462R - TSLP nGRE Complex
分子名称: DNA (5'-D(*AP*GP*CP*TP*CP*TP*CP*CP*CP*GP*GP*AP*GP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*CP*TP*CP*CP*GP*GP*GP*AP*GP*AP*GP*CP*T)-3'), Glucocorticoid receptor, ...
著者Hudson, W.H, Youn, C.E, Ortlund, E.A.
登録日2012-10-18
公開日2012-12-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.549 Å)
主引用文献The structural basis of direct glucocorticoid-mediated transrepression.
Nat.Struct.Mol.Biol., 20, 2013
5XOG
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BU of 5xog by Molmil
RNA Polymerase II elongation complex bound with Spt5 KOW5 and Elf1
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (30-MER), DNA (39-MER), ...
著者Ehara, H, Shirouzu, M, Sekine, S.
登録日2017-05-28
公開日2017-08-16
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the complete elongation complex of RNA polymerase II with basal factors
Science, 357, 2017
8CPM
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BU of 8cpm by Molmil
Human apoferritin after 405 nm laser exposure
分子名称: Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ...
著者Last, M.G.F, Noteborn, W.E.M, Sharp, T.H.
登録日2023-03-03
公開日2023-03-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (1.81 Å)
主引用文献Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
1ZOA
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BU of 1zoa by Molmil
Crystal Structure Of A328V Mutant Of The Heme Domain Of P450Bm-3 With N-Palmitoylglycine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ...
著者Hegda, A, Chen, B, Haines, D.C, Bondlela, M, Mullin, D, Graham, S.E, Tomchick, D.R, Machius, M, Peterson, J.A.
登録日2005-05-12
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation.
Biochemistry, 50, 2011
8CPX
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BU of 8cpx by Molmil
Human apoferritin after 488 nm laser exposure in presence of rsEGFP2
分子名称: Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ...
著者Last, M.G.F, Noteborn, W.E.M, Sharp, T.H.
登録日2023-03-03
公開日2023-03-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (1.76 Å)
主引用文献Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
4QBJ
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BU of 4qbj by Molmil
Crystal structure of N-myristoyl transferase from Aspergillus fumigatus complexed with a synthetic inhibitor
分子名称: 3-[[3-methyl-2-[[2,3,4-tris(fluoranyl)phenoxy]methyl]-1-benzofuran-4-yl]oxy]-N-(pyridin-3-ylmethyl)propan-1-amine, Glycylpeptide N-tetradecanoyltransferase, S-(2-OXO)PENTADECYLCOA, ...
著者Suzuki, M, Shimada, T.
登録日2014-05-08
公開日2015-04-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of N-myristoyltransferase from Aspergillus fumigatus
Acta Crystallogr.,Sect.D, 71, 2015
5A53
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BU of 5a53 by Molmil
Crystal Structure of the Rpf2-Rrs1 complex
分子名称: REGULATOR OF RIBOSOME BIOSYNTHESIS, RIBOSOME BIOGENESIS PROTEIN RPF2, SULFATE ION
著者Madru, C, Lebaron, S, Blaud, M, Delbos, L, Rety, S, Leulliot, N.
登録日2015-06-16
公開日2015-10-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Chaperoning 5S RNA Assembly.
Genes Dev., 29, 2015
8CPV
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BU of 8cpv by Molmil
Human apoferritin
分子名称: Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ...
著者Last, M.G.F, Noteborn, W.E.M, Sharp, T.H.
登録日2023-03-03
公開日2023-03-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (1.76 Å)
主引用文献Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
8CWO
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BU of 8cwo by Molmil
Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, body domain only in the local refined map
分子名称: 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Lomakin, I.B, Devarkar, S.C, Bunick, C.G.
登録日2022-05-19
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
5XRL
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BU of 5xrl by Molmil
Galectin-10/Charcot-Leyden crystal protein variant N65A crystal structure
分子名称: GLYCEROL, Galectin-10
著者Su, J.
登録日2017-06-08
公開日2018-01-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding.
Glycobiology, 28, 2018
8CPS
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BU of 8cps by Molmil
Human apoferritin
分子名称: Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ...
著者Last, M.G.F, Noteborn, W.E.M, Sharp, T.H.
登録日2023-03-03
公開日2023-03-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (1.82 Å)
主引用文献Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
8CVO
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BU of 8cvo by Molmil
Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, head domain only in the local refined map
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ...
著者Lomakin, I.B, Devarkar, S.C, Bunick, C.G.
登録日2022-05-18
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
4QEB
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BU of 4qeb by Molmil
Dcps in complex with covalent inhibitor targeting Tyrosine
分子名称: 3-{[(2,4-diaminoquinazolin-5-yl)oxy]methyl}benzenesulfonic acid, PHOSPHATE ION, m7GpppX diphosphatase
著者Liu, S.
登録日2014-05-15
公開日2015-05-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Human Dcps in complex with covalent inhibitor
To be Published
1Z2U
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BU of 1z2u by Molmil
The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance
分子名称: (R,R)-2,3-BUTANEDIOL, CHLORIDE ION, SODIUM ION, ...
著者Gavira, J.A, DiGiamamarino, E, Tempel, W, Liu, Z.J, Wang, B.C, Meehan, E, Ng, J.D, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2005-03-09
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance
To be published
4Q49
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BU of 4q49 by Molmil
Room temperature neutron crystal structure of apo human carbonic anhydrase at pH 7.5
分子名称: Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z, McKenna, R.
登録日2014-04-14
公開日2015-02-25
最終更新日2023-09-20
実験手法NEUTRON DIFFRACTION (1.8 Å)
主引用文献Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer.
Proc.Natl.Acad.Sci.USA, 112, 2015
5A3C
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BU of 5a3c by Molmil
Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes in complex with NAD
分子名称: 1,2-ETHANEDIOL, GLYCINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I.
登録日2015-05-28
公開日2015-07-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015

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