4H2I

Human ecto-5'-nucleotidase (CD73): crystal form III (closed) in complex with AMPCP

Summary for 4H2I

Entry DOI	10.2210/pdb4h2i/pdb
Related	4H1Y 4H2B 4H2F 4H2G
Descriptor	5'-nucleotidase, ZINC ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (6 entities in total)
Functional Keywords	dimer, hydrolase, phosphatase, extracellular
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	59891.98
Authors	Straeter, N.,Knapp, K.M.,Zebisch, M.,Pippel, J. (deposition date: 2012-09-12, release date: 2012-11-28, Last modification date: 2018-06-27)
Primary citation	Knapp, K.,Zebisch, M.,Pippel, J.,El-Tayeb, A.,Muller, C.E.,Strater, N. Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling. Structure, 20:2161-2173, 2012 Cited by PubMed: 23142347 DOI: 10.1016/j.str.2012.10.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation