1ADS

AN UNLIKELY SUGAR SUBSTRATE SITE IN THE 1.65 ANGSTROMS STRUCTURE OF THE HUMAN ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN DIABETIC COMPLICATIONS

Summary for 1ADS

Entry DOI	10.2210/pdb1ads/pdb
Descriptor	ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P15121
Total number of polymer chains	1
Total formula weight	36510.55
Authors	Wilson, D.K.,Quiocho, F.A. (deposition date: 1992-07-08, release date: 1993-10-31, Last modification date: 2024-02-07)
Primary citation	Wilson, D.K.,Bohren, K.M.,Gabbay, K.H.,Quiocho, F.A. An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications. Science, 257:81-84, 1992 Cited by PubMed: 1621098 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation