1DM2
 
 | | HUMAN CYCLIN-DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR HYMENIALDISINE | | 分子名称: | 1,2-ETHANEDIOL, 4-(5-AMINO-4-OXO-4H-PYRAZOL-3-YL)-2-BROMO-4,5,6,7-TETRAHYDRO-3AH-PYRROLO[2,3-C]AZEPIN-8-ONE, CYCLIN-DEPENDENT KINASE 2 | | 著者 | Thunnissen, A.M, Kim, S.-H. | | 登録日 | 1999-12-13 | | 公開日 | 2000-05-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent.
Chem.Biol., 7, 2000
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3UNK
 | | CDK2 in complex with inhibitor YL5-083 | | 分子名称: | 4-({4-[(2-chlorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid, Cyclin-dependent kinase 2, PHOSPHATE ION | | 著者 | Zhu, J.-Y, Martin, M.P, Alam, R, Schonbrunn, E. | | 登録日 | 2011-11-15 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A.
Acs Chem.Biol., 7, 2012
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1E1V
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3CTP
 | | Crystal structure of periplasmic binding protein/LacI transcriptional regulator from Alkaliphilus metalliredigens QYMF complexed with D-xylulofuranose | | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, SODIUM ION, beta-D-xylulofuranose | | 著者 | Malashkevich, V.N, Toro, R, Wasserman, S.R, Meyer, A, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-04-14 | | 公開日 | 2008-05-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Crystal structure of periplasmic binding protein/LacI transcriptional regulator from Alkaliphilus metalliredigens QYMF complexed with L-xylulose.
To be Published
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3CWG
 | | Unphosphorylated mouse STAT3 core fragment | | 分子名称: | Signal transducer and activator of transcription 3 | | 著者 | Ren, Z, Mao, X, Mertens, C, Krishnaraj, R, Qin, J, Mandal, P.K, Romanowshi, M.J, McMurray, J.S. | | 登録日 | 2008-04-21 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Crystal structure of unphosphorylated STAT3 core fragment.
Biochem.Biophys.Res.Commun., 374, 2008
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6SWI
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4G2K
 | | Crystal structure of the Marburg Virus GP2 ectodomain in its post-fusion conformation | | 分子名称: | CHLORIDE ION, GLYCEROL, General control protein GCN4, ... | | 著者 | Malashkevich, V.N, Koellhoffer, J.F, Harrison, J.S, Toro, R, Bhosle, R.C, Chandran, K, Lai, J.R, Almo, S.C. | | 登録日 | 2012-07-12 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the Marburg Virus GP2 Core Domain in Its Postfusion Conformation.
Biochemistry, 51, 2012
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4GIP
 | | Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2 | | 著者 | Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A. | | 登録日 | 2012-08-08 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4GMJ
 | | Structure of human NOT1 MIF4G domain co-crystallized with CAF1 | | 分子名称: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ... | | 著者 | Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
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4HAM
 | | Crystal Structure of Transcriptional Antiterminator from Listeria monocytogenes EGD-e | | 分子名称: | GLYCEROL, Lmo2241 protein, SULFATE ION | | 著者 | Kim, Y, Chhor, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2012-09-27 | | 公開日 | 2012-10-17 | | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | | 主引用文献 | Crystal Structure of Transcriptional Antiterminator from Listeria monocytogenes EGD-e
To be Published
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7ZP8
 | | 70S E. coli ribosome with a stalled filamin domain 5 nascent chain | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Chan, S.H.S, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | 登録日 | 2022-04-26 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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7ZQ6
 | | 70S E. coli ribosome with truncated uL23 and uL24 loops and a stalled filamin domain 5 nascent chain | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | 登録日 | 2022-04-29 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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7ZOD
 | | 70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | 登録日 | 2022-04-25 | | 公開日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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1FIN
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7ZQ5
 | | 70S E. coli ribosome with truncated uL23 and uL24 loops | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | 登録日 | 2022-04-29 | | 公開日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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3E6M
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1E1X
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3CJN
 | | Crystal structure of transcriptional regulator, MarR family, from Silicibacter pomeroyi | | 分子名称: | PHOSPHATE ION, Transcriptional regulator, MarR family | | 著者 | Chang, C, Volkart, L, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-03-13 | | 公開日 | 2008-03-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of MarR family transcriptional regulator from Silicibacter pomeroyi.
To be Published
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2HXI
 | | Structural Genomics, the crystal structure of a putative transcriptional regulator from Streptomyces coelicolor A3(2) | | 分子名称: | Putative transcriptional regulator | | 著者 | Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2006-08-03 | | 公開日 | 2006-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The crystal structure of a putative transcriptional regulator TetR from Streptomyces coelicolor A3(2)
To be Published
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1FQ1
 | | CRYSTAL STRUCTURE OF KINASE ASSOCIATED PHOSPHATASE (KAP) IN COMPLEX WITH PHOSPHO-CDK2 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CELL DIVISION PROTEIN KINASE 2, CYCLIN-DEPENDENT KINASE INHIBITOR 3, ... | | 著者 | Song, H, Hanlon, N, Brown, N.R, Noble, M.E.M, Johnson, L.N, Barford, D. | | 登録日 | 2000-09-01 | | 公開日 | 2001-05-09 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.
Mol.Cell, 7, 2001
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6T59
 | | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex | | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S. | | 登録日 | 2019-10-15 | | 公開日 | 2019-11-27 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | TTC5 mediates autoregulation of tubulin via mRNA degradation.
Science, 367, 2020
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3WBL
 | | Crystal structure of CDK2 in complex with pyrazolopyrimidine inhibitor | | 分子名称: | ACETATE ION, Cyclin-dependent kinase 2, N~7~-(4-ethoxyphenyl)-6-methyl-N~5~-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine | | 著者 | Fujino, A, Fukushima, K, Kubota, T, Kosugi, T, Takimoto-Kamimura, M. | | 登録日 | 2013-05-20 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human cyclin-dependent kinase-2 complex with MK2 inhibitor TEI-I01800: insight into the selectivity.
J.SYNCHROTRON RADIAT., 20, 2013
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1MP9
 | | TBP from a mesothermophilic archaeon, Sulfolobus acidocaldarius | | 分子名称: | TATA-binding protein | | 著者 | Koike, H, Kawashima-Ohya, Y, Yamasaki, T, Clowney, L, Katsuya, Y, Suzuki, M. | | 登録日 | 2002-09-12 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Origins of Protein Stability Revealed by Comparing Crystal Structures of TATA Binding Proteins.
Structure, 12, 2004
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7Z20
 | | 70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia and a stalled filamin domain 5 nascent chain | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | 登録日 | 2022-02-25 | | 公開日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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1FVT
 | | THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH AN OXINDOLE INHIBITOR | | 分子名称: | 4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzene-1-sulfonamide, CELL DIVISION PROTEIN KINASE 2 | | 著者 | Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K. | | 登録日 | 2000-09-20 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
Science, 291, 2001
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