4G2K

Crystal structure of the Marburg Virus GP2 ectodomain in its post-fusion conformation

Summary for 4G2K

• Entry DOI: 10.2210/pdb4g2k/pdb
• Descriptor: General control protein GCN4, Envelope glycoprotein GP2 chimera, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: gp2-gcn4 fusion, viral protein
• Biological source: Saccharomyces cerevisiae (yeast, Marburg virus); More
• Cellular location: GP2: Virion membrane ; Single-pass type I membrane protein . GP1: Virion membrane ; Peripheral membrane protein : P35254
• Total number of polymer chains: 3
• Total formula weight: 44295.34

Authors

Malashkevich, V.N.,Koellhoffer, J.F.,Harrison, J.S.,Toro, R.,Bhosle, R.C.,Chandran, K.,Lai, J.R.,Almo, S.C. (deposition date: 2012-07-12, release date: 2012-09-12, Last modification date: 2023-09-13)

• Primary citation: Koellhoffer, J.F.,Malashkevich, V.N.,Harrison, J.S.,Toro, R.,Bhosle, R.C.,Chandran, K.,Almo, S.C.,Lai, J.R.; Crystal Structure of the Marburg Virus GP2 Core Domain in Its Postfusion Conformation.; Biochemistry, 51:7665-7675, 2012; PubMed: 22935026; DOI: 10.1021/bi300976m

Experimental method

X-RAY DIFFRACTION (1.9 Å)