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6JNA
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BU of 6jna by Molmil
Cryo-EM structure of glutamate dehydrogenase from Thermococcus profundus
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutamate dehydrogenase
著者Oide, M, Kato, T, Oroguchi, T, Nakasako, M.
登録日2019-03-14
公開日2020-02-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Energy landscape of domain motion in glutamate dehydrogenase deduced from cryo-electron microscopy.
Febs J., 287, 2020
6UXE
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BU of 6uxe by Molmil
Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ...
著者Boniecki, M.T, Cygler, M.
登録日2019-11-07
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
To Be Published
6V1D
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BU of 6v1d by Molmil
Crystal structure of human trefoil factor 1
分子名称: Trefoil factor 1
著者Jarva, M.A, Lingford, J.P, John, A, Scott, N.E, Goddard-Borger, E.D.
登録日2019-11-20
公開日2019-12-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Trefoil factors share a lectin activity that defines their role in mucus.
Nat Commun, 11, 2020
7NZZ
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BU of 7nzz by Molmil
Ras1 guanine nucleotide exchange factor Cdc25 (REM and catalytic domains)
分子名称: Cell division control protein 25
著者Manso, J.A, Pereira, P.J.B, Macedo-Ribeiro, S.
登録日2021-03-24
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Pathogen-specific structural features of Candida albicans Ras1 activation complex: uncovering new antifungal drug targets
Mbio, 2023
7NS0
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BU of 7ns0 by Molmil
Bacilladnavirus capsid structure
分子名称: Capsid protein VP2
著者Munke, A, Okamoto, K.
登録日2021-03-05
公開日2022-07-20
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Primordial Capsid and Spooled ssDNA Genome Structures Unravel Ancestral Events of Eukaryotic Viruses.
Mbio, 13, 2022
6V0O
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BU of 6v0o by Molmil
PRMT5 bound to the PBM peptide from pICln
分子名称: ACETYL GROUP, Methylosome protein 50, PBM peptide, ...
著者McMillan, B.J, Raymond, D.D.
登録日2019-11-19
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol.Cell, 81, 2021
6YJG
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BU of 6yjg by Molmil
Crystal structure of MINDY1 mutant-Y114F
分子名称: Ubiquitin carboxyl-terminal hydrolase MINDY1
著者Abdul Rehman, S.A, Kulathu, Y.
登録日2020-04-03
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.
Mol.Cell, 81, 2021
6YJE
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BU of 6yje by Molmil
Plasmoodium vivax phosphoglycerate kinase bound to nitrofuran inhibitor from PEG3350 and ammonium acetate at pH 5.5
分子名称: (2~{S})-2-(5-nitrofuran-2-yl)-2,3,5,6,7,8-hexahydro-1~{H}-[1]benzothiolo[2,3-d]pyrimidin-4-one, Phosphoglycerate kinase
著者Blaszczyk, B.K, Hyvonen, M.
登録日2020-04-03
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Phosphoglycerate Kinase as a potential target for antimalarial therapy
to be published
6P0S
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BU of 6p0s by Molmil
Crystal structure of ternary DNA complex "FX2" containing E. coli Fis and phage lambda Xis
分子名称: DNA (27-MER), FX1-2, DNA-binding protein Fis, ...
著者Hancock, S.P, Cascio, D, Johnson, R.C.
登録日2019-05-17
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cooperative DNA binding by proteins through DNA shape complementarity.
Nucleic Acids Res., 47, 2019
6P7T
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BU of 6p7t by Molmil
Crystal structure of apo ToxT K231A from Vibrio cholerae strain SCE256
分子名称: Toxin co-regulated pilus virulence regulatory protein
著者Cruite, J.T, Kull, F.J.
登録日2019-06-06
公開日2020-01-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for virulence regulation inVibrio choleraeby unsaturated fatty acid components of bile.
Commun Biol, 2, 2019
7O13
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BU of 7o13 by Molmil
ABC transporter NosDFY, nucleotide-free in lipid nanodisc
分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ...
著者Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J.
登録日2021-03-28
公開日2022-11-02
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
6YRA
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BU of 6yra by Molmil
Crystal structure of ATP-dependent caprolactamase from Pseudomonas jessenii
分子名称: 5-oxoprolinase, Hydantoinase, ZINC ION
著者Rozeboom, H.J, Janssen, D.B.
登録日2020-04-20
公開日2021-04-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Catalytic and structural properties of ATP-dependent caprolactamase from Pseudomonas jessenii.
Proteins, 89, 2021
6YRU
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BU of 6yru by Molmil
Crystal structure of FAP in the dark at 100K
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid Photodecarboxylase, STEARIC ACID
著者Sorigue, D, Gotthard, G, Blangy, S, Nurizzo, D, Royant, A, Beisson, F, Arnoux, P.
登録日2020-04-20
公開日2021-04-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Mechanism and dynamics of fatty acid photodecarboxylase.
Science, 372, 2021
6VAJ
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BU of 6vaj by Molmil
Crystal Structure Analysis of human PIN1
分子名称: 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ...
著者Seo, H.-S, Dhe-Paganon, S.
登録日2019-12-17
公開日2020-12-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Nat.Chem.Biol., 17, 2021
6PAB
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BU of 6pab by Molmil
E. coli L-asparaginase II in complex with L-Asp at pH 7.0
分子名称: ASPARTIC ACID, CITRIC ACID, IMIDAZOLE, ...
著者Lubkowski, J, Wlodawer, A.
登録日2019-06-11
公開日2019-09-04
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
7OFG
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BU of 7ofg by Molmil
Oxytocin NMR solution structure
分子名称: Oxytocin
著者Shalev, D.E, Alshanski, I, Yitzchaik, S, Hurevich, M.
登録日2021-05-04
公開日2021-10-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Determining the structure and binding mechanism of oxytocin-Cu 2+ complex using paramagnetic relaxation enhancement NMR analysis.
J.Biol.Inorg.Chem., 26, 2021
6V1C
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BU of 6v1c by Molmil
Crystal structure of human trefoil factor 3 in complex with its cognate ligand
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-galactopyranose, Trefoil factor 3
著者Jarva, M.A, Lingford, J.P, John, A, Scott, N.E, Goddard-Borger, E.D.
登録日2019-11-20
公開日2019-12-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Trefoil factors share a lectin activity that defines their role in mucus.
Nat Commun, 11, 2020
6PA6
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BU of 6pa6 by Molmil
ECAII(T89V,K162T) MUTANT IN COMPLEX WITH L-ASN AT PH 8.3 in space group C2
分子名称: ASPARAGINE, IMIDAZOLE, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-06-11
公開日2019-09-04
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
7OJH
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BU of 7ojh by Molmil
ABCG2 topotecan turnover-1 state
分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ...
著者Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P.
登録日2021-05-15
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
7OJI
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BU of 7oji by Molmil
ABCG2 topotecan turnover-2 state
分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ...
著者Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P.
登録日2021-05-16
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
6PAA
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BU of 6paa by Molmil
E. coli L-asparaginase II mutant (T12V) in complex with L-Asp at pH 5.5
分子名称: ASPARTIC ACID, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-06-11
公開日2019-09-04
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
7P5C
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BU of 7p5c by Molmil
Cryo-EM structure of human TTYH3 in Ca2+ and GDN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 3
著者Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R.
登録日2021-07-14
公開日2021-08-11
最終更新日2021-09-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.
Nat Commun, 12, 2021
6PHY
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BU of 6phy by Molmil
SpAga D472N structure in complex alpha 1,3 galactobiose
分子名称: 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID, ...
著者Pluvinage, B, Boraston, A.B.
登録日2019-06-25
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system.
J.Biol.Chem., 294, 2019
6PL5
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BU of 6pl5 by Molmil
Structural coordination of polymerization and crosslinking by a peptidoglycan synthase complex
分子名称: Penicillin-binding protein 2/cell division protein FtsI, Peptidoglycan glycosyltransferase RodA, Unknown peptide
著者Sjodt, M, Rohs, P.D.A, Erlandson, S.C, Zheng, S, Rudner, D.Z, Bernhardt, T.G, Kruse, A.C.
登録日2019-06-30
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex.
Nat Microbiol, 5, 2020
6Z1Y
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BU of 6z1y by Molmil
Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK)
分子名称: SODIUM ION, Trichobakin
著者Boyko, K.M, Nikolaeva, A.Y, Britikov, V.V, Bocharov, E.V, Britikova, E.V, Le, T.B.T, Phan, C.V, Popov, V.O, Usanov, S.A.
登録日2020-05-14
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK)
To Be Published

224004

件を2024-08-21に公開中

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