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7NP1
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Crystal Structure of the SARS-CoV-2 Receptor Binding Domain in Complex with Antibody ION-360
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoblobulin light chain, Immunoglobulin gamma-1 heavy chain, ...
著者Hall, G, Cowan, R, Carr, M.
登録日2021-02-26
公開日2021-11-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.
Front Immunol, 12, 2021
5DUB
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BU of 5dub by Molmil
Context-independent anti-hypusine antibody FabHpu98 in complex with deoxyhypusine
分子名称: 1,2-ETHANEDIOL, Fab Hpu98 Heavy chain, Fab Hpu98 Light chain, ...
著者Zhai, Q, Carter, P.J.
登録日2015-09-18
公開日2016-01-20
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.
J.Mol.Biol., 428, 2016
7L2E
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BU of 7l2e by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-18 heavy chain, ...
著者Cerutti, G, Shapiro, L.
登録日2020-12-16
公開日2021-03-24
最終更新日2021-05-26
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L2F
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BU of 7l2f by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 5-24 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-24 heavy chain, ...
著者Cerutti, G, Shapiro, L.
登録日2020-12-16
公開日2021-03-24
最終更新日2021-05-26
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L2D
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BU of 7l2d by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 1-87 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称: 1-87 heavy chain, 1-87 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cerutti, G, Shapiro, L.
登録日2020-12-16
公開日2021-03-24
最終更新日2021-05-26
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7FEJ
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BU of 7fej by Molmil
Complex of FMDV A/AF/72 and bovine neutralizing scFv antibody R55
分子名称: A/AF/72 VP1, A/AF/72 VP2, A/AF/72 VP3, ...
著者He, Y, Li, K, Lou, Z.
登録日2021-07-20
公開日2021-09-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization.
J.Virol., 95, 2021
3S36
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BU of 3s36 by Molmil
Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 1121B heavy chain, 1121B light chain, Vascular endothelial growth factor receptor 2
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
3S37
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Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 1121B Fab heavy chain, 1121B Fab light chain, Vascular endothelial growth factor receptor 2
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
7UMS
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BU of 7ums by Molmil
Structure of the VP5*/VP8* assembly from the human rotavirus strain CDC-9 in complex with antibody 41 - Upright conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 41 heavy chain, ...
著者Jenni, S, Zongli, L, Wang, Y, Bessey, T, Salgado, E.N, Schmidt, A.G, Greenberg, H.B, Jiang, B, Harrison, S.C.
登録日2022-04-07
公開日2022-07-27
最終更新日2022-08-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion.
J.Virol., 96, 2022
7UCF
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BU of 7ucf by Molmil
Structure of the BG505 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCE
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BU of 7uce by Molmil
Structure of the anti-HIV-1 neutralizing antibody BG24 Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG24 Fab heavy chain, BG24 Fab light chain
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
6USF
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BU of 6usf by Molmil
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, ...
著者Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A.
登録日2019-10-26
公開日2020-04-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
7WQV
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BU of 7wqv by Molmil
Crystal structure of a neutralizing monoclonal antibody (Ab08) in complex with SARS-CoV-2 receptor-binding domain (RBD)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab08, ...
著者Zha, J, Meng, L, Zhang, X, Li, D.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy.
Plos Pathog., 19, 2023
7VYR
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BU of 7vyr by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with the D27 neutralizing antibody Fab fragment
分子名称: D27 heavy chain, D27 light chain, Spike protein S1
著者Jeong, B.-S, Oh, B.-H.
登録日2021-11-15
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants.
Mabs, 14, 2022
7S13
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BU of 7s13 by Molmil
Crystal structure of Fab in complex with mouse CD96 dimer
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, ...
著者Lee, P.S, Barman, I, Strop, P.
登録日2021-08-31
公開日2021-10-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Antibody blockade of CD96 by distinct molecular mechanisms.
Mabs, 13, 2021
7S11
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BU of 7s11 by Molmil
Crystal structure of Fab in complex with mouse CD96 monomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Lee, P.S, Chau, B, Strop, P.
登録日2021-08-31
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Antibody blockade of CD96 by distinct molecular mechanisms.
Mabs, 13, 2021
3S35
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BU of 3s35 by Molmil
Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6.64 Fab heavy chain, ...
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
5TIK
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BU of 5tik by Molmil
Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
分子名称: Cysteine-rich protective antigen
著者Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F.
登録日2016-10-03
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6, 2017
7KDM
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BU of 7kdm by Molmil
Ricin bound to VHH antibody V5G6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-RON nanobody, CHLORIDE ION, ...
著者Rudolph, M.J.
登録日2020-10-08
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.
J.Mol.Biol., 433, 2021
8ERR
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BU of 8err by Molmil
SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 heavy chain, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-10-12
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8ERQ
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BU of 8erq by Molmil
SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-10-12
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8EZ7
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BU of 8ez7 by Molmil
Structure of 1F04 Fab in complex with A/Moscow/10/1999 (H3N2) influenza virus neuraminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of influenza virus neuraminidase antibody 1F04, Light chain of influenza virus neuraminidase antibody 1F04, ...
著者Mou, Z, Lei, R, Wu, N.C, Dai, X.
登録日2022-10-31
公開日2023-11-08
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.
Immunity, 56, 2023
8EZ8
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BU of 8ez8 by Molmil
Structure of 3C08 Fab in complex with A/Moscow/10/1999 (H3N2) influenza virus neuraminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of influenza virus neuraminidase antibody 3C08, Light chain of influenza virus neuraminidase antibody 3C08, ...
著者Mou, Z, Lei, R, Wu, N.C, Dai, X.
登録日2022-10-31
公開日2023-11-08
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.
Immunity, 56, 2023
8EZ3
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BU of 8ez3 by Molmil
Structure of 3A10 Fab in complex with A/Moscow/10/1999 (H3N2) influenza virus neuraminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of influenza virus neuraminidase antibody 3A10, Light chain of influenza virus neuraminidase antibody 3A10, ...
著者Mou, Z, Lei, R, Wu, N.C, Dai, X.
登録日2022-10-31
公開日2023-11-08
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.
Immunity, 56, 2023
6C6Y
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BU of 6c6y by Molmil
Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque in complex with MERS Receptor Binding Domain
分子名称: JC57-14 Heavy chain, JC57-14 Light chain, SULFATE ION, ...
著者Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2018-01-19
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018

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