7VYR

Crystal structure of SARS-CoV-2 Spike RBD in complex with the D27 neutralizing antibody Fab fragment

Summary for 7VYR

• Entry DOI: 10.2210/pdb7vyr/pdb
• Descriptor: D27 heavy chain, D27 light chain, Spike protein S1, ... (4 entities in total)
• Functional Keywords: computational design, neutralizing antibody, sars-cov-2, viral protein, immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 164850.67

Authors

Jeong, B.-S.,Oh, B.-H. (deposition date: 2021-11-15, release date: 2022-03-02, Last modification date: 2023-11-29)

• Primary citation: Jeong, B.S.,Cha, J.S.,Hwang, I.,Kim, U.,Adolf-Bryfogle, J.,Coventry, B.,Cho, H.S.,Kim, K.D.,Oh, B.H.; Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants.; Mabs, 14:2021601-2021601, 2022; PubMed: 35030983; DOI: 10.1080/19420862.2021.2021601

Experimental method

X-RAY DIFFRACTION (2.2 Å)